Two Different Virulence-Related Regulatory Pathways in Borrelia burgdorferi Are Directly Affected by Osmotic Fluxes in the Blood Meal of Feeding Ixodes Ticks

Sébastien Bontemps-Gallo; Kevin Lawrence; Frank C. Gherardini

doi:10.1371/journal.ppat.1005791

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Open Access

Peer-reviewed

Research Article

Two Different Virulence-Related Regulatory Pathways in Borrelia burgdorferi Are Directly Affected by Osmotic Fluxes in the Blood Meal of Feeding Ixodes Ticks

Sébastien Bontemps-Gallo,

Affiliation Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
⨯
Kevin Lawrence,

Affiliation Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
⨯
Frank C. Gherardini

* E-mail: Fgherardini@niaid.nih.gov

Affiliation Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
⨯

Two Different Virulence-Related Regulatory Pathways in Borrelia burgdorferi Are Directly Affected by Osmotic Fluxes in the Blood Meal of Feeding Ixodes Ticks

Sébastien Bontemps-Gallo,
Kevin Lawrence,
Frank C. Gherardini

Published: August 15, 2016
https://doi.org/10.1371/journal.ppat.1005791

About the Authors

Sébastien Bontemps-Gallo

Affiliation Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America

Kevin Lawrence

Frank C. Gherardini

* E-mail: Fgherardini@niaid.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SBG KL FCG. Performed the experiments: SBG KL. Analyzed the data: SBG KL FCG. Wrote the paper: SBG KL FCG.

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Borrelia burgdorferi
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Gene expression
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Virulence factors
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Blood
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Nymphs
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Pathogen motility
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Cell motility
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Ticks
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