About the Authors

Damien C. Tully

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Colin B. Ogilvie

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Rebecca E. Batorsky

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

David J. Bean

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Karen A. Power

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Musie Ghebremichael

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Hunter E. Bedard

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Adrianne D. Gladden

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Aaron M. Seese

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Molly A. Amero

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Kimberly Lane

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Graham McGrath

Affiliation Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Suzane B. Bazner

Affiliation Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Jake Tinsley

Affiliation The Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America

Niall J. Lennon

Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Matthew R. Henn

Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Zabrina L. Brumme

Affiliation Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada

Philip J. Norris

Affiliation Blood Systems Research Institute, San Francisco, California, United States of America

Eric S. Rosenberg

Affiliation Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Kenneth H. Mayer

Affiliation The Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America

Heiko Jessen

Affiliation HIV Clinic Praxis, Jessen, Berlin, Germany

Sergei L. Kosakovsky Pond

Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

Bruce D. Walker

Affiliations Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

Marcus Altfeld

Affiliations Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America, Heinrich-Pette-Institut, Hamburg, Germany

Jonathan M. Carlson

Affiliation Microsoft Research, Redmond, Washington, United States of America

Todd M. Allen

tallen2@partners.org

Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: During the life of this grant, TMA’s spouse was an employee of Bristol Myers Squibb, which has a focus in Virology, specifically treatments for hepatitis B and C and HIV/AIDS. TMA’s spouse no longer works for BMS and only retained a small stock interest in the public company. TMA’s interests were reviewed and managed by Massachusetts General Hospital and Partners HealthCare in accordance with their conflict of interest policies. This does not alter our adherence to all PLOS policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DCT TMA. Performed the experiments: CBO DJB KAP HEB ADG AMS. Analyzed the data: DCT CBO DJB SLKP MG JMC. Contributed reagents/materials/analysis tools: REB SLKP JMC MAA KL GM SBB JT NJL MRH ZLB PJN ESR KHM HJ BDW MA. Wrote the paper: DCT TMA SLKP ZLB JMC.