About the Authors

Glen M. Chew

Affiliation Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America

Tsuyoshi Fujita

Affiliations Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America, Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan

Gabriela M. Webb

Affiliations Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America, Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America

Benjamin J. Burwitz

Affiliations Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America, Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America

Helen L. Wu

Affiliations Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America, Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America

Jason S. Reed

Affiliations Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America, Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America

Katherine B. Hammond

Affiliations Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America, Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America

Kiera L. Clayton

Affiliation Department of Immunology, University of Toronto, Toronto, Ontario, Canada

Naoto Ishii

Affiliation Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan

Mohamed Abdel-Mohsen

Affiliation Division of Experimental Medicine, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America

Teri Liegler

Affiliation Division of Experimental Medicine, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America

Brooks I. Mitchell

Affiliation Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America

Frederick M. Hecht

Affiliation HIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America

Mario Ostrowski

Affiliation Department of Immunology, University of Toronto, Toronto, Ontario, Canada

Cecilia M. Shikuma

Affiliation Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America

Scott G. Hansen

Affiliations Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America, Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America

Mark Maurer

Affiliation Biologics Discovery California, Bristol-Myers Squibb, Redwood City, California, United States of America

Alan J. Korman

Affiliation Biologics Discovery California, Bristol-Myers Squibb, Redwood City, California, United States of America

Steven G. Deeks

Affiliation HIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America

Jonah B. Sacha

‡ JBS and LCN share equal co-senior authorship.

Affiliations Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America, Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America

Lishomwa C. Ndhlovu

lndhlovu@hawaii.edu

‡ JBS and LCN share equal co-senior authorship.

Affiliation Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America

Competing Interests

I hereby declare that MM (Scientist, Immuno-Oncology) and AJK (Vice president, Immuno-Oncology) are employed by Bristol-Myers Squibb, and have no significant competing financial, professional or personal interests that might have influenced the performance or presentation of the work described in this manuscript. This does not alter our adherence to all PLOS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GMC LCN JBS. Performed the experiments: GMC GMW TF BJB JSR HLW KBH BIM LCN JBS. Analyzed the data: GMC CMS KLC MO NI TL FMH MAM SGH MM AJK SGD JBS. Contributed reagents/materials/analysis tools: GMW BJB MM AJK KLC TF MAM. Wrote the paper: GMC CMS KLC MO NI TL FMH MAM SGH MM AJK SGD JBS LCN.