Cryptosporidium Lactate Dehydrogenase Is Associated with the Parasitophorous Vacuole Membrane and Is a Potential Target for Developing Therapeutics

Haili Zhang; Fengguang Guo; Guan Zhu

doi:10.1371/journal.ppat.1005250

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Open Access

Peer-reviewed

Research Article

Cryptosporidium Lactate Dehydrogenase Is Associated with the Parasitophorous Vacuole Membrane and Is a Potential Target for Developing Therapeutics

Haili Zhang ,

Contributed equally to this work with: Haili Zhang, Fengguang Guo

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America
⨯
Fengguang Guo ,

Contributed equally to this work with: Haili Zhang, Fengguang Guo

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America
⨯
Guan Zhu

* E-mail: gzhu@cvm.tamu.edu

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America
⨯

Cryptosporidium Lactate Dehydrogenase Is Associated with the Parasitophorous Vacuole Membrane and Is a Potential Target for Developing Therapeutics

Haili Zhang,
Fengguang Guo,
Guan Zhu

Published: November 12, 2015
https://doi.org/10.1371/journal.ppat.1005250

About the Authors

Haili Zhang

Contributed equally to this work with: Haili Zhang, Fengguang Guo

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America

Fengguang Guo

Contributed equally to this work with: Haili Zhang, Fengguang Guo

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America

Guan Zhu

* E-mail: gzhu@cvm.tamu.edu

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GZ HZ FG. Performed the experiments: HZ FG. Analyzed the data: GZ HZ FG. Wrote the paper: GZ HZ FG.

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Cryptosporidium parvum
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Sporozoites
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Oocysts
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Parasitic diseases
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Host cells
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Recombinant proteins
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Antibodies
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Merozoites
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