Global Analysis of Mouse Polyomavirus Infection Reveals Dynamic Regulation of Viral and Host Gene Expression and Promiscuous Viral RNA Editing

Seth B. Garren; Yuvabharath Kondaveeti; Michael O. Duff; Gordon G. Carmichael

doi:10.1371/journal.ppat.1005166

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Open Access

Peer-reviewed

Research Article

Global Analysis of Mouse Polyomavirus Infection Reveals Dynamic Regulation of Viral and Host Gene Expression and Promiscuous Viral RNA Editing

Seth B. Garren,

Affiliation Department of Genetics and Genome Sciences, UCONN Health, Farmington, Connecticut, United States of America
⨯
Yuvabharath Kondaveeti,

Affiliation Department of Genetics and Genome Sciences, UCONN Health, Farmington, Connecticut, United States of America
⨯
Michael O. Duff,

Affiliation Department of Genetics and Genome Sciences, UCONN Health, Farmington, Connecticut, United States of America
⨯
Gordon G. Carmichael

* E-mail: carmichael@uchc.edu

Affiliation Department of Genetics and Genome Sciences, UCONN Health, Farmington, Connecticut, United States of America
⨯

Global Analysis of Mouse Polyomavirus Infection Reveals Dynamic Regulation of Viral and Host Gene Expression and Promiscuous Viral RNA Editing

Seth B. Garren,
Yuvabharath Kondaveeti,
Michael O. Duff,
Gordon G. Carmichael

Published: September 25, 2015
https://doi.org/10.1371/journal.ppat.1005166

About the Authors

Seth B. Garren

Affiliation Department of Genetics and Genome Sciences, UCONN Health, Farmington, Connecticut, United States of America

Yuvabharath Kondaveeti

Affiliation Department of Genetics and Genome Sciences, UCONN Health, Farmington, Connecticut, United States of America

Michael O. Duff

Affiliation Department of Genetics and Genome Sciences, UCONN Health, Farmington, Connecticut, United States of America

Gordon G. Carmichael

* E-mail: carmichael@uchc.edu

Affiliation Department of Genetics and Genome Sciences, UCONN Health, Farmington, Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GGC SBG. Performed the experiments: SBG MOD YK. Analyzed the data: GGC SBG MOD YK. Contributed reagents/materials/analysis tools: GGC MOD. Wrote the paper: SBG GGC.

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Mammalian genomics
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Sequence alignment
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DNA replication
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Polyadenylation
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RNA alignment
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DNA transcription
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Virus effects on host gene expression
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Gene regulation
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