Knocking on Closed Doors: Host Interferons Dynamically Regulate Blood-Brain Barrier Function during Viral Infections of the Central Nervous System

Brian P. Daniels; Robyn S. Klein

doi:10.1371/journal.ppat.1005096

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Knocking on Closed Doors: Host Interferons Dynamically Regulate Blood-Brain Barrier Function during Viral Infections of the Central Nervous System

Brian P. Daniels,

Affiliation Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Robyn S. Klein

* E-mail: rklein@dom.wustl.edu

Affiliations Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯

Knocking on Closed Doors: Host Interferons Dynamically Regulate Blood-Brain Barrier Function during Viral Infections of the Central Nervous System

Brian P. Daniels,
Robyn S. Klein

Published: September 17, 2015
https://doi.org/10.1371/journal.ppat.1005096

About the Authors

Brian P. Daniels

Affiliation Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Robyn S. Klein

* E-mail: rklein@dom.wustl.edu

Affiliations Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Competing Interests

The authors have declared that no competing interests exist.

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Central nervous system
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Blood-brain barrier
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Interferons
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West Nile virus
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Viral transmission and infection
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Inflammation
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Viral pathogens
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