About the Authors
- Emmanuel A. Asante
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Andrew Grimshaw
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Michelle Smidak
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Tatiana Jakubcova
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Andrew Tomlinson
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Asif Jeelani
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Shyma Hamdan
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Caroline Powell
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Susan Joiner
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Jacqueline M. Linehan
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Sebastian Brandner
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- Jonathan D. F. Wadsworth
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Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
- John Collinge
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* E-mail: j.collinge@prion.ucl.ac.uk
Affiliation MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
Competing Interests
JC is a Director and JC and JDFW are shareholders of D-Gen Limited, an academic spin-out company working in the field of prion disease diagnosis, decontamination and therapeutics. D-Gen owns the ICSM 18 and ICSM 35 antibodies used in this study. This does not alter our adherence to all PLOS policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: EAA JDFW JC. Performed the experiments: EAA AG MS TJ AT AJ SH CP SJ JML SB. Analyzed the data: EAA JDFW SB JC. Wrote the paper: EAA JDFW JC.