About the Authors

Monica A. McArthur

Affiliation Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Stephanie Fresnay

Affiliation Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Laurence S. Magder

Affiliation Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Thomas C. Darton

Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the National Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom

Claire Jones

Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the National Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom

Claire S. Waddington

Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the National Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom

Christoph J. Blohmke

Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the National Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom

Gordon Dougan

Affiliation Microbial Pathogenesis Group, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Brian Angus

Affiliation Nuffield Department of Medicine, University of Oxford, United Kingdom

Myron M. Levine

Affiliation Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Andrew J. Pollard

Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the National Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom

Marcelo B. Sztein

msztein@medicine.umaryland.edu

Affiliation Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MAM SF MBS. Performed the experiments: MAM SF. Analyzed the data: MAM SF LSM MBS. Contributed reagents/materials/analysis tools: TCD CSW CJ CJB BA. Wrote the paper: MAM SF LSM TCD CJ CSW CJB GD BA MML AJP MBS. Set up challenge model and generated clinical data: TCD CSW GD MML AJP.