Early Virus-Host Interactions Dictate the Course of a Persistent Infection

Brian M. Sullivan; John R. Teijaro; Juan Carlos de la Torre; Michael B. A. Oldstone

doi:10.1371/journal.ppat.1004588

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Open Access

Peer-reviewed

Research Article

Early Virus-Host Interactions Dictate the Course of a Persistent Infection

Brian M. Sullivan ,

* E-mail: bsully@scripps.edu

Affiliation Viral-Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
⨯
John R. Teijaro,

Affiliation Viral-Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
⨯
Juan Carlos de la Torre,

Affiliation Viral-Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
⨯
Michael B. A. Oldstone

Affiliation Viral-Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
⨯

Early Virus-Host Interactions Dictate the Course of a Persistent Infection

Brian M. Sullivan,
John R. Teijaro,
Juan Carlos de la Torre,
Michael B. A. Oldstone

Published: January 8, 2015
https://doi.org/10.1371/journal.ppat.1004588

About the Authors

Brian M. Sullivan

* E-mail: bsully@scripps.edu

Affiliation Viral-Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

John R. Teijaro

Affiliation Viral-Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Juan Carlos de la Torre

Affiliation Viral-Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Michael B. A. Oldstone

Affiliation Viral-Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BMS JRT JCT MBAO. Performed the experiments: BMS. Analyzed the data: BMS JRT JCT MBAO. Contributed reagents/materials/analysis tools: BMS JRT JCT MBAO. Wrote the paper: BMS JRT JCT MBAO.

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Immune response
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Viral persistence and latency
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Spleen
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T cells
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Cytokines
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Antibodies
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Flow cytometry
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Antiviral immune response
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