Systemic Expression of Kaposi Sarcoma Herpesvirus (KSHV) Vflip in Endothelial Cells Leads to a Profound Proinflammatory Phenotype and Myeloid Lineage Remodeling In Vivo

Gianna Ballon; Gunkut Akar; Ethel Cesarman

doi:10.1371/journal.ppat.1004581

Loading metrics

Open Access

Peer-reviewed

Research Article

Systemic Expression of Kaposi Sarcoma Herpesvirus (KSHV) Vflip in Endothelial Cells Leads to a Profound Proinflammatory Phenotype and Myeloid Lineage Remodeling In Vivo

Gianna Ballon ,

* E-mail: gballon@nshs.edu, ballongianna@gmail.com (GB); ecesarm@med.cornell.edu (EC)

Affiliation Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, United States of America
⨯
Gunkut Akar,

Affiliation Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, United States of America
⨯
Ethel Cesarman

* E-mail: gballon@nshs.edu, ballongianna@gmail.com (GB); ecesarm@med.cornell.edu (EC)

Affiliation Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, United States of America
⨯

Systemic Expression of Kaposi Sarcoma Herpesvirus (KSHV) Vflip in Endothelial Cells Leads to a Profound Proinflammatory Phenotype and Myeloid Lineage Remodeling In Vivo

Gianna Ballon,
Gunkut Akar,
Ethel Cesarman

Published: January 21, 2015
https://doi.org/10.1371/journal.ppat.1004581

About the Authors

Gianna Ballon

* E-mail: gballon@nshs.edu, ballongianna@gmail.com (GB); ecesarm@med.cornell.edu (EC)

Affiliation Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, United States of America

Gunkut Akar

Affiliation Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, United States of America

Ethel Cesarman

* E-mail: gballon@nshs.edu, ballongianna@gmail.com (GB); ecesarm@med.cornell.edu (EC)

Affiliation Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GB EC. Performed the experiments: GB GA. Analyzed the data: GB EC. Contributed reagents/materials/analysis tools: GB GA. Wrote the paper: GB EC.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Endothelial cells
Is the Subject Area "Endothelial cells" applicable to this article?

Thanks for your feedback.
Bone marrow cells
Is the Subject Area "Bone marrow cells" applicable to this article?

Thanks for your feedback.
B cells
Is the Subject Area "B cells" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Kaposi's sarcoma-associated herpesvirus
Is the Subject Area "Kaposi's sarcoma-associated herpesvirus" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.
Kaposi sarcoma
Is the Subject Area "Kaposi sarcoma" applicable to this article?

Thanks for your feedback.