P47phox−/− Mice Are Compromised in Expansion and Activation of CD8+ T Cells and Susceptible to Trypanosoma cruzi Infection

Monisha Dhiman; Nisha Jain Garg

doi:10.1371/journal.ppat.1004516

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Open Access

Peer-reviewed

Research Article

P47^phox−/− Mice Are Compromised in Expansion and Activation of CD8⁺ T Cells and Susceptible to Trypanosoma cruzi Infection

Monisha Dhiman ,

* E-mail: monisha.dhiman@gmail.com (MD); nigarg@utmb.edu (NJG)

Current address: Center for Genetic Diseases and Molecular Medicine, School of Emerging Life Science Technologies, Central University of Punjab, Bathinda, Punjab, India

Affiliation Department of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, Texas, United States of America
⨯
Nisha Jain Garg

* E-mail: monisha.dhiman@gmail.com (MD); nigarg@utmb.edu (NJG)

Affiliations Department of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, Texas, United States of America, Department of Pathology, UTMB, Galveston, Texas, United States of America, Institute for Human Infections and Immunity, UTMB, Galveston, Texas, United States of America
⨯

P47^phox−/− Mice Are Compromised in Expansion and Activation of CD8⁺ T Cells and Susceptible to Trypanosoma cruzi Infection

Monisha Dhiman,
Nisha Jain Garg

Published: December 4, 2014
https://doi.org/10.1371/journal.ppat.1004516

About the Authors

Monisha Dhiman

* E-mail: monisha.dhiman@gmail.com (MD); nigarg@utmb.edu (NJG)

Current address: Center for Genetic Diseases and Molecular Medicine, School of Emerging Life Science Technologies, Central University of Punjab, Bathinda, Punjab, India

Affiliation Department of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, Texas, United States of America

Nisha Jain Garg

* E-mail: monisha.dhiman@gmail.com (MD); nigarg@utmb.edu (NJG)

Affiliations Department of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, Texas, United States of America, Department of Pathology, UTMB, Galveston, Texas, United States of America, Institute for Human Infections and Immunity, UTMB, Galveston, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

All addressed above. Conceived and designed the experiments: MD NJG. Performed the experiments: MD. Analyzed the data: MD NJG. Contributed reagents/materials/analysis tools: NJG. Wrote the paper: MD NJG.

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Trypanosoma cruzi
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Parasitic diseases
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Macrophages
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Cytotoxic T cells
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Inflammation
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Cytokines
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T cells
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Nitric oxide
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