About the Authors

Andrea A. Berry

Contributed equally to this work with: Andrea A. Berry, Yi Yang, Natalia Pakharukova

Affiliation Center for Vaccine Development, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Yi Yang

Contributed equally to this work with: Andrea A. Berry, Yi Yang, Natalia Pakharukova

Affiliation Centre for Structural Biology, Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom

Natalia Pakharukova

Contributed equally to this work with: Andrea A. Berry, Yi Yang, Natalia Pakharukova

Affiliation Department of Chemistry, University of Turku, Turku, JBL, Arcanum, Turku, Finland

James A. Garnett

Affiliation Centre for Structural Biology, Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom

Wei-chao Lee

Affiliation Centre for Structural Biology, Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom

Ernesto Cota

Affiliation Centre for Structural Biology, Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom

Jan Marchant

Affiliation Centre for Structural Biology, Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom

Saumendra Roy

Affiliations Department of Chemistry, University of Turku, Turku, JBL, Arcanum, Turku, Finland, Department of Chemistry and Biotechnology, Swedish University of Agricultural Sciences, Uppsala BioCentre, Uppsala, Sweden

Minna Tuittila

Affiliation Department of Chemistry, University of Turku, Turku, JBL, Arcanum, Turku, Finland

Bing Liu

Affiliation Centre for Structural Biology, Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom

Keith G. Inman

Affiliation Paragon Bioservices, Inc, Baltimore, Maryland, United States of America

Fernando Ruiz-Perez

Affiliation Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia, United States of America

Inacio Mandomando

Affiliation Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia, United States of America

James P. Nataro

Affiliation Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia, United States of America

Anton V. Zavialov

anton.zavialov@utu.fi (AVZ); s.j.matthews@imperial.ac.uk (SM)

Affiliation Department of Chemistry, University of Turku, Turku, JBL, Arcanum, Turku, Finland

Steve Matthews

anton.zavialov@utu.fi (AVZ); s.j.matthews@imperial.ac.uk (SM)

Affiliation Centre for Structural Biology, Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist. Although Keith G. Inman is employed by Paragon Bioservices Inc, this does not alter our adherence to all PLOS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AAB YY NP JAG IM JPN AVZ SM. Performed the experiments: AAB YY NP JAG WcL JPN SR MT BL KGI FRP IM. Analyzed the data: AAB YY NP JAG JM BL KGI FRP IM JPN AVZ SM. Contributed reagents/materials/analysis tools: EC JM IM JPN AVZ SM. Wrote the paper: AAB YY JAG EC KGI FRP IM JPN AVZ SM.