Late Engagement of CD86 after Influenza Virus Clearance Promotes Recovery in a FoxP3+ Regulatory T Cell Dependent Manner

Emily K. Moser; Matthew M. Hufford; Thomas J. Braciale

doi:10.1371/journal.ppat.1004315

Loading metrics

Open Access

Peer-reviewed

Research Article

Late Engagement of CD86 after Influenza Virus Clearance Promotes Recovery in a FoxP3⁺ Regulatory T Cell Dependent Manner

Emily K. Moser,

Affiliations The Beirne B. Carter Center for Immunology Research, The University of Virginia, Charlottesville, Virginia, United States of America, Department of Pharmacology, The University of Virginia, Charlottesville, Virginia, United States of America
⨯
Matthew M. Hufford,

Affiliations The Beirne B. Carter Center for Immunology Research, The University of Virginia, Charlottesville, Virginia, United States of America, Department of Microbiology, The University of Virginia, Charlottesville, Virginia, United States of America
⨯
Thomas J. Braciale

* E-mail: tjb2r@virginia.edu

Affiliations The Beirne B. Carter Center for Immunology Research, The University of Virginia, Charlottesville, Virginia, United States of America, Department of Microbiology, The University of Virginia, Charlottesville, Virginia, United States of America, Department of Pathology, The University of Virginia, Charlottesville, Virginia, United States of America
⨯

Late Engagement of CD86 after Influenza Virus Clearance Promotes Recovery in a FoxP3⁺ Regulatory T Cell Dependent Manner

Emily K. Moser,
Matthew M. Hufford,
Thomas J. Braciale

Published: August 21, 2014
https://doi.org/10.1371/journal.ppat.1004315

About the Authors

Emily K. Moser

Affiliations The Beirne B. Carter Center for Immunology Research, The University of Virginia, Charlottesville, Virginia, United States of America, Department of Pharmacology, The University of Virginia, Charlottesville, Virginia, United States of America

Matthew M. Hufford

Affiliations The Beirne B. Carter Center for Immunology Research, The University of Virginia, Charlottesville, Virginia, United States of America, Department of Microbiology, The University of Virginia, Charlottesville, Virginia, United States of America

Thomas J. Braciale

* E-mail: tjb2r@virginia.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EKM MMH TJB. Performed the experiments: EKM MMH. Analyzed the data: EKM MMH. Contributed reagents/materials/analysis tools: TJB. Contributed to the writing of the manuscript: EKM. Manuscript Revision: EKM MMH TJB.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Regulatory T cells
Is the Subject Area "Regulatory T cells" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Influenza A virus
Is the Subject Area "Influenza A virus" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Neutrophils
Is the Subject Area "Neutrophils" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
CD coreceptors
Is the Subject Area "CD coreceptors" applicable to this article?

Thanks for your feedback.