Establishment of Murine Gammaherpesvirus Latency in B Cells Is Not a Stochastic Event

Jérémie Decalf; Cristina Godinho-Silva; Diana Fontinha; Sofia Marques; J. Pedro Simas

doi:10.1371/journal.ppat.1004269

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Open Access

Peer-reviewed

Research Article

Establishment of Murine Gammaherpesvirus Latency in B Cells Is Not a Stochastic Event

Jérémie Decalf ,

Contributed equally to this work with: Jérémie Decalf, Cristina Godinho-Silva

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal
⨯
Cristina Godinho-Silva ,

Contributed equally to this work with: Jérémie Decalf, Cristina Godinho-Silva

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal
⨯
Diana Fontinha,

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal
⨯
Sofia Marques,

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal
⨯
J. Pedro Simas

* E-mail: psimas@fm.ul.pt

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal
⨯

Establishment of Murine Gammaherpesvirus Latency in B Cells Is Not a Stochastic Event

Jérémie Decalf,
Cristina Godinho-Silva,
Diana Fontinha,
Sofia Marques,
J. Pedro Simas

Published: July 31, 2014
https://doi.org/10.1371/journal.ppat.1004269

About the Authors

Jérémie Decalf

Contributed equally to this work with: Jérémie Decalf, Cristina Godinho-Silva

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

Cristina Godinho-Silva

Contributed equally to this work with: Jérémie Decalf, Cristina Godinho-Silva

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

Diana Fontinha

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

Sofia Marques

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

J. Pedro Simas

* E-mail: psimas@fm.ul.pt

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JD CGS SM JPS. Performed the experiments: JD CGS DF SM. Analyzed the data: JD CGS DF SM JPS. Wrote the paper: JD JPS.

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B cells
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Viral persistence and latency
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Spleen
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Enzyme-linked immunoassays
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Cell differentiation
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Plasma cells
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T cells
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Yellow fluorescent protein
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