About the Authors

Emma Hodcroft

Affiliation Institute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, Edinburgh, United Kingdom

Jarrod D. Hadfield

Affiliation Institute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, Edinburgh, United Kingdom

Esther Fearnhill

Affiliation MRC Clinical Trials Unit Aviation House, London, United Kingdom

Andrew Phillips

Affiliation Infection and Population Health, University College London, Royal Free Hospital, London, United Kingdom

David Dunn

Affiliation MRC Clinical Trials Unit Aviation House, London, United Kingdom

Siobhan O'Shea

Affiliation Department of Infectious Diseases, King's College London, London, United Kingdom

Deenan Pillay

Affiliation Research Department of Infection, University College London, London, United Kingdom

Andrew J. Leigh Brown

A.Leigh-Brown@ed.ac.uk

Affiliation Institute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, Edinburgh, United Kingdom

on behalf of the UK HIV Drug Resistance Database and the UK CHIC Study

Membership of the UK HIV Drug Resistance Database and the UK CHIC Study is provided at the end of this paper.

Competing Interests

Additional support for the UK HIV Resistance Database is provided by Boehringer Ingelheim, Bristol-Myers Squibb, Gilead, Tibotec (a division of Janssen-Cilag) and Roche. Although some authors have received funding from various commercial organizations for research, travel grants, speaking engagements or consultancy fees, neither those organizations nor the study funders had any role in study design, data collection and analysis, decision to publish, or preparation of the manuscript and this does not alter our adherence to all PLOS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: EH JDH AP AJLB. Performed the experiments: EF SO. Analyzed the data: EH JDH EF AJLB. Contributed reagents/materials/analysis tools: JDH SO DD DP. Wrote the paper: EH JDH AJLB.