Regulation of Human T-Lymphotropic Virus Type I Latency and Reactivation by HBZ and Rex

Subha Philip; Muhammad Atif Zahoor; Huijun Zhi; Yik-Khuan Ho; Chou-Zen Giam

doi:10.1371/journal.ppat.1004040

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Open Access

Peer-reviewed

Research Article

Regulation of Human T-Lymphotropic Virus Type I Latency and Reactivation by HBZ and Rex

Subha Philip,

Affiliation Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
⨯
Muhammad Atif Zahoor,

Affiliation Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
⨯
Huijun Zhi,

Affiliation Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
⨯
Yik-Khuan Ho,

Affiliation Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
⨯
Chou-Zen Giam

* E-mail: chou-zen.giam@usuhs.edu

Affiliation Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
⨯

Regulation of Human T-Lymphotropic Virus Type I Latency and Reactivation by HBZ and Rex

Subha Philip,
Muhammad Atif Zahoor,
Huijun Zhi,
Yik-Khuan Ho,
Chou-Zen Giam

Published: April 3, 2014
https://doi.org/10.1371/journal.ppat.1004040

About the Authors

Subha Philip

Affiliation Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America

Muhammad Atif Zahoor

Affiliation Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America

Huijun Zhi

Affiliation Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America

Yik-Khuan Ho

Affiliation Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America

Chou-Zen Giam

* E-mail: chou-zen.giam@usuhs.edu

Affiliation Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CZG SP. Performed the experiments: SP MAZ HZ YKH. Analyzed the data: CZG SP MAZ HZ YKH. Contributed reagents/materials/analysis tools: HZ YKH. Wrote the paper: CZG SP.

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HTLV-1
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Low income countries
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Transcription factors
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Cloning
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Messenger RNA
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Viral replication
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Ligation independent cloning
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Viral persistence and latency
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