About the Authors

Anat Melamed

Affiliation Section of Immunology, Imperial College London, Wright-Fleming Institute, London, United Kingdom

Aviva D. Witkover

Affiliation Section of Immunology, Imperial College London, Wright-Fleming Institute, London, United Kingdom

Daniel J. Laydon

Affiliation Section of Immunology, Imperial College London, Wright-Fleming Institute, London, United Kingdom

Rachael Brown

Affiliation Section of Immunology, Imperial College London, Wright-Fleming Institute, London, United Kingdom

Kristin Ladell

Affiliation Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom

Kelly Miners

Affiliation Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom

Aileen G. Rowan

Affiliation Section of Immunology, Imperial College London, Wright-Fleming Institute, London, United Kingdom

Niall Gormley

Affiliation Illumina, Little Chesterford, Essex, United Kingdom

David A. Price

Affiliation Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom

Graham P. Taylor

Affiliation Section of Infectious Diseases, Imperial College London, Wright-Fleming Institute, London, United Kingdom

Edward L. Murphy

Affiliation Departments of Laboratory Medicine and Epidemiology/Biostatistics, University of California San Francisco and Blood Systems Research Institute, San Francisco, California, United States of America

Charles R. M. Bangham

c.bangham@imperial.ac.uk

Affiliation Section of Immunology, Imperial College London, Wright-Fleming Institute, London, United Kingdom

Competing Interests

Niall Gormley is an employee of Illumina Inc, a public company that develops and markets systems for genetic analysis. This does not alter our adherence to all PLOS policies on sharing data and materials. The remaining authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AM NG DAP GPT CRMB. Performed the experiments: AM ADW RB KL KM AGR. Analyzed the data: AM DJL. Contributed reagents/materials/analysis tools: ELM GPT. Wrote the paper: AM DAP CRMB.