About the Authors

Paul W. Denton

Affiliation Division of Infectious Diseases, Department of Medicine, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Julie M. Long

Affiliation Division of Infectious Diseases, Department of Medicine, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Stephen W. Wietgrefe

Affiliation Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, United States of America

Craig Sykes

Affiliation Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Rae Ann Spagnuolo

Affiliation Division of Infectious Diseases, Department of Medicine, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Olivia D. Snyder

Affiliation Division of Infectious Diseases, Department of Medicine, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Katherine Perkey

Affiliation Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, United States of America

Nancie M. Archin

Affiliation Division of Infectious Diseases, Department of Medicine, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Shailesh K. Choudhary

Affiliation Division of Infectious Diseases, Department of Medicine, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Kuo Yang

Affiliation Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Michael G. Hudgens

Affiliation Department of Biostatistics, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Ira Pastan

Affiliation Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Ashley T. Haase

Affiliation Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, United States of America

Angela D. Kashuba

Affiliation Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Edward A. Berger

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

David M. Margolis

Affiliation Division of Infectious Diseases, Department of Medicine, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

J. Victor Garcia

victor_garcia@med.unc.edu

Affiliation Division of Infectious Diseases, Department of Medicine, UNC Center for AIDS Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Competing Interests

Dr. Berger and Dr. Pastan report that they are co-inventors on several immunotoxin issued patents and patent applications. This does not alter our adherence to all PLOS policies on sharing data and materials. All other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PWD JVG. Performed the experiments: PWD JML SWW CS RAS ODS KP. Analyzed the data: PWD SWW CS KY MGH ATH ADK JVG. Contributed reagents/materials/analysis tools: IP EAB. Wrote the paper: PWD EAB JVG. Provided preliminary data and intellectual input: NMA SKC DMM.