Global Rescue of Defects in HIV-1 Envelope Glycoprotein Incorporation: Implications for Matrix Structure

Philip R. Tedbury; Sherimay D. Ablan; Eric O. Freed

doi:10.1371/journal.ppat.1003739

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Open Access

Peer-reviewed

Research Article

Global Rescue of Defects in HIV-1 Envelope Glycoprotein Incorporation: Implications for Matrix Structure

Philip R. Tedbury,

Affiliation Virus-Cell Interaction Section, HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Sherimay D. Ablan,

Affiliation Virus-Cell Interaction Section, HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Eric O. Freed

* E-mail: efreed@nih.gov

Affiliation Virus-Cell Interaction Section, HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯

Global Rescue of Defects in HIV-1 Envelope Glycoprotein Incorporation: Implications for Matrix Structure

Philip R. Tedbury,
Sherimay D. Ablan,
Eric O. Freed

Published: November 14, 2013
https://doi.org/10.1371/journal.ppat.1003739

About the Authors

Philip R. Tedbury

Affiliation Virus-Cell Interaction Section, HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Sherimay D. Ablan

Affiliation Virus-Cell Interaction Section, HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Eric O. Freed

* E-mail: efreed@nih.gov

Affiliation Virus-Cell Interaction Section, HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PRT EOF. Performed the experiments: PRT SDA. Analyzed the data: PRT SDA EOF. Contributed reagents/materials/analysis tools: PRT SDA. Wrote the paper: PRT EOF.

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Viral replication
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HIV-1
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Crystal structure
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Virions
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Point mutation
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Molecular cloning
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293T cells
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Transfection
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