Identification of Trans-Sialidases as a Common Mediator of Endothelial Cell Activation by African Trypanosomes

Zeinab Ammar; Nicolas Plazolles; Théo Baltz; Virginie Coustou

doi:10.1371/journal.ppat.1003710

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Open Access

Peer-reviewed

Research Article

Identification of Trans-Sialidases as a Common Mediator of Endothelial Cell Activation by African Trypanosomes

Zeinab Ammar,

Affiliation French National Centre for Scientific Research (CNRS), Université Bordeaux Segalen, Microbiologie fondamentale et Pathogénicité, UMR 5234, Bordeaux, France
⨯
Nicolas Plazolles,

Affiliation French National Centre for Scientific Research (CNRS), Université Bordeaux Segalen, Microbiologie fondamentale et Pathogénicité, UMR 5234, Bordeaux, France
⨯
Théo Baltz,

Affiliation French National Centre for Scientific Research (CNRS), Université Bordeaux Segalen, Microbiologie fondamentale et Pathogénicité, UMR 5234, Bordeaux, France
⨯
Virginie Coustou

* E-mail: virginie.coustou@u-bordeaux2.fr

Affiliation French National Centre for Scientific Research (CNRS), Université Bordeaux Segalen, Microbiologie fondamentale et Pathogénicité, UMR 5234, Bordeaux, France
⨯

Identification of Trans-Sialidases as a Common Mediator of Endothelial Cell Activation by African Trypanosomes

Zeinab Ammar,
Nicolas Plazolles,
Théo Baltz,
Virginie Coustou

Published: October 10, 2013
https://doi.org/10.1371/journal.ppat.1003710

About the Authors

Zeinab Ammar

Affiliation French National Centre for Scientific Research (CNRS), Université Bordeaux Segalen, Microbiologie fondamentale et Pathogénicité, UMR 5234, Bordeaux, France

Nicolas Plazolles

Affiliation French National Centre for Scientific Research (CNRS), Université Bordeaux Segalen, Microbiologie fondamentale et Pathogénicité, UMR 5234, Bordeaux, France

Théo Baltz

Affiliation French National Centre for Scientific Research (CNRS), Université Bordeaux Segalen, Microbiologie fondamentale et Pathogénicité, UMR 5234, Bordeaux, France

Virginie Coustou

* E-mail: virginie.coustou@u-bordeaux2.fr

Affiliation French National Centre for Scientific Research (CNRS), Université Bordeaux Segalen, Microbiologie fondamentale et Pathogénicité, UMR 5234, Bordeaux, France

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VC ZA. Performed the experiments: ZA NP VC. Analyzed the data: ZA VC. Contributed reagents/materials/analysis tools: ZA VC NP TB. Wrote the paper: ZA VC TB.

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Trypanosoma
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Endothelial cells
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Transcription factors
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Lectins
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Inflammation
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Trypanosoma congolense
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Host-pathogen interactions
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Trypanosoma vivax
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