The Late Endosomal HOPS Complex Anchors Active G-Protein Signaling Essential for Pathogenesis in Magnaporthe oryzae

Ravikrishna Ramanujam; Meredith E. Calvert; Poonguzhali Selvaraj; Naweed I. Naqvi

doi:10.1371/journal.ppat.1003527

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Open Access

Peer-reviewed

Research Article

The Late Endosomal HOPS Complex Anchors Active G-Protein Signaling Essential for Pathogenesis in Magnaporthe oryzae

Ravikrishna Ramanujam,

Affiliations Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore, School of Biological Sciences, Nanyang Technological University, Singapore, Singapore
⨯
Meredith E. Calvert,

Affiliation Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
⨯
Poonguzhali Selvaraj,

Affiliation Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
⨯
Naweed I. Naqvi

* E-mail: naweed@tll.org.sg

Affiliations Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore, School of Biological Sciences, Nanyang Technological University, Singapore, Singapore, Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
⨯

The Late Endosomal HOPS Complex Anchors Active G-Protein Signaling Essential for Pathogenesis in Magnaporthe oryzae

Ravikrishna Ramanujam,
Meredith E. Calvert,
Poonguzhali Selvaraj,
Naweed I. Naqvi

Published: August 1, 2013
https://doi.org/10.1371/journal.ppat.1003527

About the Authors

Ravikrishna Ramanujam

Affiliations Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore, School of Biological Sciences, Nanyang Technological University, Singapore, Singapore

Meredith E. Calvert

Affiliation Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore

Poonguzhali Selvaraj

Affiliation Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore

Naweed I. Naqvi

* E-mail: naweed@tll.org.sg

Affiliations Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore, School of Biological Sciences, Nanyang Technological University, Singapore, Singapore, Department of Biological Sciences, National University of Singapore, Singapore, Singapore.

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NIN. Performed the experiments: RR MEC PS. Analyzed the data: RR MEC NIN. Contributed reagents/materials/analysis tools: NIN. Wrote the paper: RR NIN.

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G-protein signaling
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Appressoria
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Endosomes
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Cell membranes
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cAMP signaling cascade
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Pathogenesis
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Rice blast fungus
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Vacuoles
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