The Production of Monokaryotic Hyphae by Cryptococcus neoformans Can Be Induced by High Temperature Arrest of the Cell Cycle and Is Independent of Same-Sex Mating

Jianmin Fu; Ian R. Morris; Brian L. Wickes

doi:10.1371/journal.ppat.1003335

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Open Access

Peer-reviewed

Research Article

The Production of Monokaryotic Hyphae by Cryptococcus neoformans Can Be Induced by High Temperature Arrest of the Cell Cycle and Is Independent of Same-Sex Mating

Jianmin Fu,

Affiliation The Department of Microbiology and Immunology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Ian R. Morris,

Affiliation The Department of Microbiology and Immunology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Brian L. Wickes

* E-mail: wickes@uthscsa.edu

Affiliation The Department of Microbiology and Immunology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯

The Production of Monokaryotic Hyphae by Cryptococcus neoformans Can Be Induced by High Temperature Arrest of the Cell Cycle and Is Independent of Same-Sex Mating

Jianmin Fu,
Ian R. Morris,
Brian L. Wickes

Published: May 2, 2013
https://doi.org/10.1371/journal.ppat.1003335

About the Authors

Jianmin Fu

Affiliation The Department of Microbiology and Immunology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

Ian R. Morris

Affiliation The Department of Microbiology and Immunology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

Brian L. Wickes

* E-mail: wickes@uthscsa.edu

Affiliation The Department of Microbiology and Immunology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BLW JF. Performed the experiments: JF. Analyzed the data: BLW JF. Contributed reagents/materials/analysis tools: JF IRM. Wrote the paper: BLW JF.

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Cryptococcus neoformans
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Cell cycle and cell division
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Seeds
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Cell fusion
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Fungal pathogens
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Ploidy
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Cell staining
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Yeast
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