About the Authors

Pankaj Pal

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Kimberly A. Dowd

Affiliation Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

James D. Brien

Affiliation Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

Melissa A. Edeling

Affiliation Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Sergey Gorlatov

Affiliation MacroGenics, Rockville, Maryland, United States of America

Syd Johnson

Affiliation MacroGenics, Rockville, Maryland, United States of America

Iris Lee

Affiliation Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

Wataru Akahata

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Gary J. Nabel

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Mareike K. S. Richter

Affiliation Department of Medical Microbiology, Molecular Virology Section (HPC EB88), University Medical Center Groningen and University of Groningen, Groningen, Netherlands

Jolanda M. Smit

Affiliation Department of Medical Microbiology, Molecular Virology Section (HPC EB88), University Medical Center Groningen and University of Groningen, Groningen, Netherlands

Daved H. Fremont

Affiliations Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Theodore C. Pierson

Affiliation Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Mark T. Heise

Affiliation Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Michael S. Diamond

diamond@borcim.wustl.edu

Affiliations Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Competing Interests

I have read the journal's policy and have the following conflicts: S. Johnson and S. Gorlatov are employees of MacroGenics, which has an option for licensure of the anti-CHKV MAbs for commercial development. M. Diamond is a paid consultant for MacroGenics. This does not alter our adherence to all PLoS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: PP KAD JDB TCP JMS MTH DHF MSD. Performed the experiments: PP KAD IL MAE SG MKSR MTH. Analyzed the data: PP KAD TCP MAE JMS SG SJ MTH MSD. Contributed reagents/materials/analysis tools: WA GJN. Wrote the paper: PP MSD KAD TCP WA GJN MTH.