About the Authors

Chikara Kaito

kaito@mol.f.u-tokyo.ac.jp.

Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Yuki Saito

Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Mariko Ikuo

Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Yosuke Omae

Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Han Mao

Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Gentaro Nagano

Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Tomoko Fujiyuki

Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Shunsuke Numata

Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Xiao Han

Affiliation Department of Infection Control Science, Graduate School of Medicine, Juntendo University, Tokyo, Japan

Kazuaki Obata

Affiliation Sekino Hospital, Tokyo, Japan

Setsuo Hasegawa

Affiliation Sekino Clinical Pharmacology Clinic, Tokyo, Japan

Hiroki Yamaguchi

Affiliation Division of Hematology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan

Koiti Inokuchi

Affiliation Division of Hematology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan

Teruyo Ito

Affiliation Department of Infection Control Science, Graduate School of Medicine, Juntendo University, Tokyo, Japan

Keiichi Hiramatsu

Affiliation Department of Infection Control Science, Graduate School of Medicine, Juntendo University, Tokyo, Japan

Kazuhisa Sekimizu

Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Competing Interests

We have received part of our funding from Genome Pharmaceutical Institute and have an agreement with them on taking patents. However, this does not alter our adherence to all PLoS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CK. Performed the experiments: CK YS MI YO HM GN TF SN XH. Analyzed the data: CK YS MI YO HM GN TF SN XH. Contributed reagents/materials/analysis tools: KO SH HY KI TI KH. Wrote the paper: CK KS.