About the Authors

Yuhong Huang

Contributed equally to this work with: Yuhong Huang, Yan Huang

Current address: Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Yan Huang

Contributed equally to this work with: Yuhong Huang, Yan Huang

Affiliations Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Yimin Fang

Affiliation Guangzhou Chest Hospital, Guangzhou, China

Juan Wang

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Yan Li

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Nan Wang

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Jianbo Zhang

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Ming Gao

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Lirong Huang

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Fangfang Yang

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Cong Wang

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Shuxian Lin

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Yanan Yao

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Liangliang Ren

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Yi Chen

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Xuanjing Du

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Dan Xie

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

Rongshun Wu

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

Kouxing Zhang

Affiliation The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

Lifang Jiang

jianglf@mail.sysu.edu.cn (Lifang Jiang); yuxb@mail.sysu.edu.cn (Xinbing Yu); laixm@mail.sysu.edu.cn (Xiaomin Lai)

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Xinbing Yu

jianglf@mail.sysu.edu.cn (Lifang Jiang); yuxb@mail.sysu.edu.cn (Xinbing Yu); laixm@mail.sysu.edu.cn (Xiaomin Lai)

Affiliations Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Xiaomin Lai

jianglf@mail.sysu.edu.cn (Lifang Jiang); yuxb@mail.sysu.edu.cn (Xinbing Yu); laixm@mail.sysu.edu.cn (Xiaomin Lai)

Affiliations Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China, Key Laboratory of Tropical Diseases Control, Ministry of Education; Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province; Guangdong Provincial Research Center for Severe Infectious Disease Prevention and Control Technology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: Xiaomin Lai, Xinbing Yu, and Lifang Jiang. Performed the experiments: Yuhong Huang, Yan Huang, Yimin Fang, Juan Wang, Yan Li, Nan Wang, Jianbo Zhang, Ming Gao, Lirong Huang, Fangfang Yang, Cong Wang, Shuxian Lin, Yanan Yao, Liangliang Ren, Yi Chen, Xuanjing Du, Dan Xie, and Rongshun Wu. Analyzed the data: Xiaomin Lai, Yuhong Huang, Yan Huang, Juan Wang, and Nan Wang. Contributed reagents/materials/analysis tools: Yuhong Huang, Yan Huang, Yimin Fang, Yan Li, and Kouxing Zhang. Wrote the paper: Xiaomin Lai, Yuhong Huang, and Yan Huang.