The Respiratory Syncytial Virus Polymerase Has Multiple RNA Synthesis Activities at the Promoter

Sarah L. Noton; Laure R. Deflubé; Chadene Z. Tremaglio; Rachel Fearns

doi:10.1371/journal.ppat.1002980

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Open Access

Peer-reviewed

Research Article

The Respiratory Syncytial Virus Polymerase Has Multiple RNA Synthesis Activities at the Promoter

Sarah L. Noton ,

Contributed equally to this work with: Sarah L. Noton, Laure R. Deflubé

Affiliation Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Laure R. Deflubé ,

Contributed equally to this work with: Sarah L. Noton, Laure R. Deflubé

Affiliation Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Chadene Z. Tremaglio,

Affiliation Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Rachel Fearns

* E-mail: rfearns@bu.edu

Affiliation Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯

The Respiratory Syncytial Virus Polymerase Has Multiple RNA Synthesis Activities at the Promoter

Sarah L. Noton,
Laure R. Deflubé,
Chadene Z. Tremaglio,
Rachel Fearns

Published: October 18, 2012
https://doi.org/10.1371/journal.ppat.1002980

About the Authors

Sarah L. Noton

Contributed equally to this work with: Sarah L. Noton, Laure R. Deflubé

Affiliation Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America

Laure R. Deflubé

Contributed equally to this work with: Sarah L. Noton, Laure R. Deflubé

Affiliation Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America

Chadene Z. Tremaglio

Affiliation Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America

Rachel Fearns

* E-mail: rfearns@bu.edu

Affiliation Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SLN LRD CZT RF. Performed the experiments: SLN LRD CZT. Analyzed the data: SLN LRD CZT RF. Wrote the paper: SLN RF.

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RNA synthesis
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Genomics
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RNA analysis
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Polymerases
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RNA structure
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Oligonucleotides
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Viral replication
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Viral packaging
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