DNA Mutations Mediate Microevolution between Host-Adapted Forms of the Pathogenic Fungus Cryptococcus neoformans

Denise A. Magditch; Tong-Bao Liu; Chaoyang Xue; Alexander Idnurm

doi:10.1371/journal.ppat.1002936

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Open Access

Peer-reviewed

Research Article

DNA Mutations Mediate Microevolution between Host-Adapted Forms of the Pathogenic Fungus Cryptococcus neoformans

Denise A. Magditch,

Affiliation Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri, United States of America
⨯
Tong-Bao Liu,

Affiliation Public Health Research Institute Center, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
⨯
Chaoyang Xue,

Affiliation Public Health Research Institute Center, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
⨯
Alexander Idnurm

* E-mail: idnurma@umkc.edu

Affiliation Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri, United States of America
⨯

DNA Mutations Mediate Microevolution between Host-Adapted Forms of the Pathogenic Fungus Cryptococcus neoformans

Denise A. Magditch,
Tong-Bao Liu,
Chaoyang Xue,
Alexander Idnurm

Published: October 4, 2012
https://doi.org/10.1371/journal.ppat.1002936

About the Authors

Denise A. Magditch

Affiliation Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri, United States of America

Tong-Bao Liu

Affiliation Public Health Research Institute Center, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

Chaoyang Xue

Affiliation Public Health Research Institute Center, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

Alexander Idnurm

* E-mail: idnurma@umkc.edu

Affiliation Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DAM T-BL CX AI. Performed the experiments: DAM T-BL CX AI. Analyzed the data: DAM T-BL CX AI. Wrote the paper: DAM T-BL CX AI.

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Mouse models
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