About the Authors

Subrata Barman

Affiliation Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Petr S. Krylov

Affiliation Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Thomas P. Fabrizio

Affiliation Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

John Franks

Affiliation Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Jasmine C. Turner

Affiliation Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Patrick Seiler

Affiliation Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

David Wang

Affiliation Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Jerold E. Rehg

Affiliation Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Gene A. Erickson

Affiliation Veterinary Diagnostic Laboratory (NCVDL) System, North Carolina Department of Agriculture, Raleigh, North Carolina, United States of America

Marie Gramer

Affiliation Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, United States of America

Robert G. Webster

Affiliation Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Richard J. Webby

Richard.webby@stjude.org

Affiliation Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Competing Interests

Dr. Webster receives funding from F. Hoffmann LaRoche Ltd., but the funds were not used in support of the research presented in the manuscript. This does not alter our adherence to all PLoS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SB RGW RJW. Performed the experiments: SB PSK TPF JF JCT PS DW JER. Analyzed the data: SB RGW RJW JER. Contributed reagents/materials/analysis tools: JER. Wrote the paper: SB RGW RJW GAE MG. Conducted experiments with ferrets: SB PSK TPF JF JCT PS DW. Sequenced the TRS viruses: SB PSK TPF. Isolation and initial characterization of the TRS viruses: GAE MG. Ferret lung pathology and data analysis: JER.