About the Authors

Alex T. Chen

Current address: Infectious and Inflammatory disease Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

Affiliation Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Markus Cornberg

Current address: Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

Affiliation Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Stephanie Gras

Affiliation Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia

Carole Guillonneau

Current address: CR2-CNRS, INSERM U643-ITERT, CHU Hotel-Dieu, Nantes, France

Affiliation Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia

Jamie Rossjohn

Affiliation Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia

Andrew Trees

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Sebastien Emonet

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Juan C. de la Torre

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Raymond M. Welsh

raymond.welsh@umassmed.edu

Affiliation Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Liisa K. Selin

Affiliation Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ATC, MC, RMW, LKS, SG, CG, JR, AT, SE, and JCT all participated in conceiving and designing the experiments. Performed the experiments: ATC, MC, RMW, and LKS did the infections, T cell analyses, immune pathology, and wrote the paper. SG, CG, and JR performed the peptide-MHC structural studies. AT, SE, and JCT generated by reverse genetics the recombinant viruses. Analyzed the data: ATC MC RMW LKS SG CG JR AT SE JCT. Wrote the paper: ATC RMW. JCT designed and contributed recombinant viruses or this work.