About the Authors

Laura McCulloch

Affiliation The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Midlothian, United Kingdom

Karen L. Brown

Affiliation The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Midlothian, United Kingdom

Barry M. Bradford

Affiliation The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Midlothian, United Kingdom

John Hopkins

Affiliation The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Midlothian, United Kingdom

Mick Bailey

Affiliation Division of Veterinary Pathology, Infection and Immunity, School of Clinical Veterinary Science, University of Bristol, Avon, United Kingdom

Klaus Rajewsky

Affiliation Program in Cellular and Molecular Medicine, Children's Hospital, and Immune Disease Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Jean C. Manson

Affiliation The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Midlothian, United Kingdom

Neil A. Mabbott

neil.mabbott@roslin.ed.ac.uk

Affiliation The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Midlothian, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NAM LM BMB KLB JCM KR JH MB. Performed the experiments: LM KLB NAM. Analyzed the data: LM NAM MB JH. Contributed reagents/materials/analysis tools: MB JCM KR. Wrote the paper: NAM LM BMB KLB JCM KR MB JH.