BosR (BB0647) Controls the RpoN-RpoS Regulatory Pathway and Virulence Expression in Borrelia burgdorferi by a Novel DNA-Binding Mechanism

Zhiming Ouyang; Ranjit K. Deka; Michael V. Norgard

doi:10.1371/journal.ppat.1001272

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Peer-reviewed

Research Article

BosR (BB0647) Controls the RpoN-RpoS Regulatory Pathway and Virulence Expression in Borrelia burgdorferi by a Novel DNA-Binding Mechanism

Zhiming Ouyang,

Affiliation Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Ranjit K. Deka,

Affiliation Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Michael V. Norgard

* E-mail: michael.norgard@utsouthwestern.edu

Affiliation Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯

BosR (BB0647) Controls the RpoN-RpoS Regulatory Pathway and Virulence Expression in Borrelia burgdorferi by a Novel DNA-Binding Mechanism

Zhiming Ouyang,
Ranjit K. Deka,
Michael V. Norgard

Published: February 10, 2011
https://doi.org/10.1371/journal.ppat.1001272

About the Authors

Zhiming Ouyang

Affiliation Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Ranjit K. Deka

Affiliation Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Michael V. Norgard

* E-mail: michael.norgard@utsouthwestern.edu

Affiliation Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZO MVN. Performed the experiments: ZO. Analyzed the data: ZO MVN. Contributed reagents/materials/analysis tools: RKD. Wrote the paper: ZO MVN.

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Regulator genes
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Electrophoretic mobility shift assay
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Gene expression
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Gene regulation
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DNA-binding proteins
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Cloning
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Integral membrane proteins
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Complement system
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