High-Resolution Functional Mapping of the Venezuelan Equine Encephalitis Virus Genome by Insertional Mutagenesis and Massively Parallel Sequencing

Brett F. Beitzel; Russell R. Bakken; Jeffrey M. Smith; Connie S. Schmaljohn

doi:10.1371/journal.ppat.1001146

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Open Access

Peer-reviewed

Research Article

High-Resolution Functional Mapping of the Venezuelan Equine Encephalitis Virus Genome by Insertional Mutagenesis and Massively Parallel Sequencing

Brett F. Beitzel,

Affiliation The United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Russell R. Bakken,

Affiliation The United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Jeffrey M. Smith,

Affiliation The United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Connie S. Schmaljohn

* E-mail: connie.schmaljohn@us.army.mil

Affiliation The United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯

High-Resolution Functional Mapping of the Venezuelan Equine Encephalitis Virus Genome by Insertional Mutagenesis and Massively Parallel Sequencing

Brett F. Beitzel,
Russell R. Bakken,
Jeffrey M. Smith,
Connie S. Schmaljohn

Published: October 14, 2010
https://doi.org/10.1371/journal.ppat.1001146

About the Authors

Brett F. Beitzel

Affiliation The United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America

Russell R. Bakken

Affiliation The United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America

Jeffrey M. Smith

Affiliation The United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America

Connie S. Schmaljohn

* E-mail: connie.schmaljohn@us.army.mil

Affiliation The United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BFB CSS. Performed the experiments: BFB RRB JMS. Analyzed the data: BFB. Contributed reagents/materials/analysis tools: BFB. Wrote the paper: BFB CSS.

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Mammalian genomics
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Transposable elements
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Viral replication
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Nucleotide sequencing
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Genomic libraries
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Viral genomics
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Genomics
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RNA sequencing
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