Inclusion Biogenesis and Reactivation of Persistent Chlamydia trachomatis Requires Host Cell Sphingolipid Biosynthesis

D. Kesley Robertson; Ling Gu; Regina K. Rowe; Wandy L. Beatty

doi:10.1371/journal.ppat.1000664

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Open Access

Peer-reviewed

Research Article

Inclusion Biogenesis and Reactivation of Persistent Chlamydia trachomatis Requires Host Cell Sphingolipid Biosynthesis

D. Kesley Robertson,

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Ling Gu,

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Regina K. Rowe,

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Wandy L. Beatty

* E-mail: beatty@borcim.wustl.edu

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯

Inclusion Biogenesis and Reactivation of Persistent Chlamydia trachomatis Requires Host Cell Sphingolipid Biosynthesis

D. Kesley Robertson,
Ling Gu,
Regina K. Rowe,
Wandy L. Beatty

Published: November 20, 2009
https://doi.org/10.1371/journal.ppat.1000664

About the Authors

D. Kesley Robertson

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Ling Gu

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Regina K. Rowe

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Wandy L. Beatty

* E-mail: beatty@borcim.wustl.edu

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DKR RKR WLB. Performed the experiments: DKR LG RKR WLB. Analyzed the data: DKR LG RKR WLB. Wrote the paper: WLB.

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Chlamydia infection
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Lipid inclusions
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Host cells
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Chlamydia trachomatis
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Chlamydia
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Biosynthesis
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Intracellular pathogens
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Intracellular membranes
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