About the Authors

Michael M. Klein

Contributed equally to this work with: Michael M. Klein, Apostolos G. Gittis

Affiliation Structural Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

Apostolos G. Gittis

Contributed equally to this work with: Michael M. Klein, Apostolos G. Gittis

Affiliation Structural Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

Hua-Poo Su

Current address: Merck & Co., Inc., West Point, Pennsylvania, United States of America

Affiliation Structural Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

Morris O. Makobongo

Affiliation Malaria Vaccine Development Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

Jaime M. Moore

Current address: University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Affiliation Structural Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

Sanjay Singh

Current address: Gennova Biopharmaceuticals Limited, Pune, Maharashtra, India

Affiliation Malaria Vaccine Development Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

Louis H. Miller

Affiliation Malaria Vaccine Development Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

David N. Garboczi

dgarboczi@niaid.nih.gov

Affiliation Structural Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Expressed MC179, prepared MC179 crystals, collected X-ray data, analyzed the structure, and wrote the manuscript: MMK. Interpreted the electron density and built and refined the MC179 model: AGG. Expressed MC179 and collected X-ray data: H-PS. Planned and performed the flow cytometry experiments: MOM JMM. Planned and supervised the flow cytometry experiments: SS LHM. Planned experiments, expressed MC179, processed X-ray data, calculated experimental electron density maps, analyzed the structure, and wrote the manuscript: DNG.