Enzymatic Properties of the Neuraminidase of Seasonal H1N1 Influenza Viruses Provide Insights for the Emergence of Natural Resistance to Oseltamivir

Marie-Anne Rameix-Welti; Vincent Enouf; Frédérique Cuvelier; Patricia Jeannin; Sylvie van der Werf

doi:10.1371/journal.ppat.1000103

Loading metrics

Open Access

Opinion articles provide a forum for expression of views, and responses to previous statements, on a range of topical, emerging and controversial issues.

See all article types »

Enzymatic Properties of the Neuraminidase of Seasonal H1N1 Influenza Viruses Provide Insights for the Emergence of Natural Resistance to Oseltamivir

Marie-Anne Rameix-Welti,

Affiliation Unité de Génétique Moléculaire des Virus Respiratoires, URA3015 CNRS, EA302 Université Paris Diderot, Paris, France
⨯
Vincent Enouf,

Affiliation National Influenza Center (Northern-France), Institut Pasteur, Paris, France
⨯
Frédérique Cuvelier,

Affiliation National Influenza Center (Northern-France), Institut Pasteur, Paris, France
⨯
Patricia Jeannin,

Affiliation National Influenza Center (Northern-France), Institut Pasteur, Paris, France
⨯
Sylvie van der Werf

* E-mail: svdwerf@pasteur.fr

Affiliations Unité de Génétique Moléculaire des Virus Respiratoires, URA3015 CNRS, EA302 Université Paris Diderot, Paris, France, National Influenza Center (Northern-France), Institut Pasteur, Paris, France
⨯

Enzymatic Properties of the Neuraminidase of Seasonal H1N1 Influenza Viruses Provide Insights for the Emergence of Natural Resistance to Oseltamivir

Marie-Anne Rameix-Welti,
Vincent Enouf,
Frédérique Cuvelier,
Patricia Jeannin,
Sylvie van der Werf

Published: July 25, 2008
https://doi.org/10.1371/journal.ppat.1000103

About the Authors

Marie-Anne Rameix-Welti

Affiliation Unité de Génétique Moléculaire des Virus Respiratoires, URA3015 CNRS, EA302 Université Paris Diderot, Paris, France

Vincent Enouf

Affiliation National Influenza Center (Northern-France), Institut Pasteur, Paris, France

Frédérique Cuvelier

Affiliation National Influenza Center (Northern-France), Institut Pasteur, Paris, France

Patricia Jeannin

Affiliation National Influenza Center (Northern-France), Institut Pasteur, Paris, France

Sylvie van der Werf

* E-mail: svdwerf@pasteur.fr

Affiliations Unité de Génétique Moléculaire des Virus Respiratoires, URA3015 CNRS, EA302 Université Paris Diderot, Paris, France, National Influenza Center (Northern-France), Institut Pasteur, Paris, France

Competing Interests

The authors have declared that no competing interests exist.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

H1N1
Is the Subject Area "H1N1" applicable to this article?

Thanks for your feedback.
Influenza viruses
Is the Subject Area "Influenza viruses" applicable to this article?

Thanks for your feedback.
Viral vaccines
Is the Subject Area "Viral vaccines" applicable to this article?

Thanks for your feedback.
Influenza
Is the Subject Area "Influenza" applicable to this article?

Thanks for your feedback.
Enzyme kinetics
Is the Subject Area "Enzyme kinetics" applicable to this article?

Thanks for your feedback.
H5N1
Is the Subject Area "H5N1" applicable to this article?

Thanks for your feedback.
Influenza A virus
Is the Subject Area "Influenza A virus" applicable to this article?

Thanks for your feedback.
Viral transmission and infection
Is the Subject Area "Viral transmission and infection" applicable to this article?

Thanks for your feedback.