Evidence for Direct Involvement of the Capsid Protein in HIV Infection of Nondividing Cells

Masahiro Yamashita; Omar Perez; Thomas J Hope; Michael Emerman

doi:10.1371/journal.ppat.0030156

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Open Access

Peer-reviewed

Research Article

Evidence for Direct Involvement of the Capsid Protein in HIV Infection of Nondividing Cells

Masahiro Yamashita,

Affiliation Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Omar Perez,

Affiliation Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Thomas J Hope,

Affiliation Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
⨯
Michael Emerman

*To whom correspondence should be addressed. E-mail: memerman@fhcrc.org

Affiliation Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯

Evidence for Direct Involvement of the Capsid Protein in HIV Infection of Nondividing Cells

Masahiro Yamashita,
Omar Perez,
Thomas J Hope,
Michael Emerman

Published: October 26, 2007
https://doi.org/10.1371/journal.ppat.0030156

About the Authors

Masahiro Yamashita

Affiliation Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Omar Perez

Affiliation Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois, United States of America

Thomas J Hope

Affiliation Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

Michael Emerman

*To whom correspondence should be addressed. E-mail: memerman@fhcrc.org

Affiliation Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

All authors conceived and designed the experiments, analyzed the data, and wrote the paper. MY, OP, and ME performed the experiments. MY and ME contributed reagents/materials/analysis tools.

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HIV
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HIV-1
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Reverse transcription
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Virions
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HIV infections
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Viral core
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Viral replication
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Virus uncoating
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