RNAi Screen in Drosophila Cells Reveals the Involvement of the Tom Complex in Chlamydia Infection

Isabelle Derré; Marc Pypaert; Alice Dautry-Varsat; Hervé Agaisse

doi:10.1371/journal.ppat.0030155

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Open Access

Peer-reviewed

Research Article

RNAi Screen in Drosophila Cells Reveals the Involvement of the Tom Complex in Chlamydia Infection

Isabelle Derré ,

*To whom correspondence should be addressed. E-mail: isabelle.derre@yale.edu

Affiliation Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven Connecticut, United States of America
⨯
Marc Pypaert,

Affiliations Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, United States of America , Center for Cell and Molecular Imaging, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Alice Dautry-Varsat,

Affiliations Unité de Biologie des Interactions Cellulaires, Institut Pasteur, Paris, France , CNRS URA 2582, Paris, France
⨯
Hervé Agaisse

Affiliation Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven Connecticut, United States of America
⨯

RNAi Screen in Drosophila Cells Reveals the Involvement of the Tom Complex in Chlamydia Infection

Isabelle Derré,
Marc Pypaert,
Alice Dautry-Varsat,
Hervé Agaisse

Published: October 26, 2007
https://doi.org/10.1371/journal.ppat.0030155

About the Authors

Isabelle Derré

*To whom correspondence should be addressed. E-mail: isabelle.derre@yale.edu

Affiliation Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven Connecticut, United States of America

Marc Pypaert

Affiliations Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, United States of America , Center for Cell and Molecular Imaging, Yale University School of Medicine, New Haven, Connecticut, United States of America

Alice Dautry-Varsat

Affiliations Unité de Biologie des Interactions Cellulaires, Institut Pasteur, Paris, France , CNRS URA 2582, Paris, France

Hervé Agaisse

Affiliation Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

ID conceived and designed the experiments, performed the experiments, and wrote the paper. ID and MP analyzed the data. MP, ADV, and HA contributed reagents/materials/analysis tools.

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Chlamydia infection
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Drosophila melanogaster
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Chlamydia trachomatis
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Mitochondria
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Chlamydia
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Small interfering RNA
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Host cells
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Cell differentiation
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