Synergy or Independence? Deciphering the Interaction of HLA Class I and NK Cell KIR Alleles in Early HIV-1 Disease Progression

Jason D Barbour; Uma Sriram; Stacy J Caillier; Jay A Levy; Frederick M Hecht; Jorge R Oksenberg

doi:10.1371/journal.ppat.0030043

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Synergy or Independence? Deciphering the Interaction of HLA Class I and NK Cell KIR Alleles in Early HIV-1 Disease Progression

Jason D Barbour ,

*To whom correspondence should be addressed. E-mail: jbarbour@php.ucsf.edu
⨯
Uma Sriram,
Stacy J Caillier,
Jay A Levy,
Frederick M Hecht,
Jorge R Oksenberg

Synergy or Independence? Deciphering the Interaction of HLA Class I and NK Cell KIR Alleles in Early HIV-1 Disease Progression

Jason D Barbour,
Uma Sriram,
Stacy J Caillier,
Jay A Levy,
Frederick M Hecht,
Jorge R Oksenberg

Published: April 20, 2007
https://doi.org/10.1371/journal.ppat.0030043

About the Authors

Jason D Barbour: *To whom correspondence should be addressed. E-mail: jbarbour@php.ucsf.edu
Uma Sriram
Stacy J Caillier
Jay A Levy
Frederick M Hecht
Jorge R Oksenberg

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JDB, JAL, FMH, and JRO designed the study. US, SJC, and JRO performed experiments. JDB analyzed the data. US, SJC, FMH, and JRO contributed reagents or tools. JDB, JAL, FMH, and JRO wrote the paper.

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T cells
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HIV-1
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Viral load
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NK cells
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Alleles
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Antiretroviral therapy
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Cytotoxic T cells
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Infectious disease control
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