H-NS Mediates the Silencing of Laterally Acquired Genes in Bacteria

Sacha Lucchini; Gary Rowley; Martin D Goldberg; Douglas Hurd; Marcus Harrison; Jay C. D Hinton

doi:10.1371/journal.ppat.0020081

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Open Access

Peer-reviewed

Research Article

H-NS Mediates the Silencing of Laterally Acquired Genes in Bacteria

Sacha Lucchini,

Affiliation Molecular Microbiology Group, Institute of Food Research, Colney, Norwich, United Kingdom
⨯
Gary Rowley,

Affiliation Molecular Microbiology Group, Institute of Food Research, Colney, Norwich, United Kingdom
⨯
Martin D Goldberg,

¤ Current address: School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Affiliation Molecular Microbiology Group, Institute of Food Research, Colney, Norwich, United Kingdom
⨯
Douglas Hurd,

Affiliation Oxford Gene Technology, Yarnton, Oxford, United Kingdom
⨯
Marcus Harrison,

Affiliation Oxford Gene Technology, Yarnton, Oxford, United Kingdom
⨯
Jay C. D Hinton

*To whom correspondence should be addressed. E-mail: jay.hinton@bbsrc.ac.uk

Affiliation Molecular Microbiology Group, Institute of Food Research, Colney, Norwich, United Kingdom
⨯

H-NS Mediates the Silencing of Laterally Acquired Genes in Bacteria

Sacha Lucchini,
Gary Rowley,
Martin D Goldberg,
Douglas Hurd,
Marcus Harrison,
Jay C. D Hinton

Published: August 18, 2006
https://doi.org/10.1371/journal.ppat.0020081

About the Authors

Sacha Lucchini

Affiliation Molecular Microbiology Group, Institute of Food Research, Colney, Norwich, United Kingdom

Gary Rowley

Affiliation Molecular Microbiology Group, Institute of Food Research, Colney, Norwich, United Kingdom

Martin D Goldberg

¤ Current address: School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Affiliation Molecular Microbiology Group, Institute of Food Research, Colney, Norwich, United Kingdom

Douglas Hurd

Affiliation Oxford Gene Technology, Yarnton, Oxford, United Kingdom

Marcus Harrison

Affiliation Oxford Gene Technology, Yarnton, Oxford, United Kingdom

Jay C. D Hinton

*To whom correspondence should be addressed. E-mail: jay.hinton@bbsrc.ac.uk

Affiliation Molecular Microbiology Group, Institute of Food Research, Colney, Norwich, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SL and JCDH conceived and designed the experiments. SL, GR, and MDG performed the experiments. SL analyzed the data. DH and MH contributed reagents/materials/analysis tools. SL and JCDH wrote the paper.

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Salmonella typhimurium
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Gene expression
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DNA-binding proteins
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DNA
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RNA polymerase
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Oligonucleotides
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Pathogenesis
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Gene regulation
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