About the Authors

Stuart J. D Neil

Affiliation Aaron Diamond AIDS Research Center and Laboratory of Retrovirology, Rockefeller University, New York, New York, United States of America

Scott W Eastman

Affiliation Aaron Diamond AIDS Research Center and Laboratory of Retrovirology, Rockefeller University, New York, New York, United States of America

Nolwenn Jouvenet

Affiliation Aaron Diamond AIDS Research Center and Laboratory of Retrovirology, Rockefeller University, New York, New York, United States of America

Paul D Bieniasz

To whom correspondence should be addressed. E-mail: pbienias@adarc.org

Affiliation Aaron Diamond AIDS Research Center and Laboratory of Retrovirology, Rockefeller University, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SJDN and PDB conceived the study, evaluated the data, and wrote the paper. SJDN performed the experiments with the following exceptions. SWE constructed and characterized the Rab5a mutants and their effects, together with the effects of Vpu on transferrin uptake. NJ constructed the L-domain mutants of HIV-1 Gag-CFP and determined their subcellular localization in HeLa cells.