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Trypanosoma brucei

Comparative maxicircle analysis in Trypanosoma species from the LSRM clade highlights patterns in an underexplored lineage

Fanny Rusman, Valeria Aramayo, Noelia Floridia-Yapur, Anahí Guadalupe Díaz, Tatiana Ponce, Soledad Hodi, Juan José Aguirre, Gonzalo Greif, Luisa Berná, Carlos Robello, Patricio Diosque, Nicolás Tomasini

published 22 Sep 2025

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An independently tunable dual control system for RNAi complementation in Trypanosoma brucei

Raveen Armstrong, Matt J. Romprey, Henry M. Raughley, Stephanie B. Delzell, Matthew P. Frost, James Chambers, Grace G. Garman, David Anaguano, Michele M. Klingbeil

published 12 May 2025

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Distinct modes of interaction within eIF4F-like complexes and susceptibility to the RocA inhibitor for the Trypanosoma brucei EIF4AI translation initiation factor

Danielle M. N. Moura, Amanda L. Soares, Adalúcia da Silva, João L. A. B. Ribeiro, Jack D. Sunter, Ludmila A. Assis, Mark Carrington, Osvaldo P. de Melo Neto

published 09 May 2025

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Trypanosomes lack a canonical EJC but possess an UPF1 dependent NMD-like pathway

Bernardo Papini Gabiatti, Eden Ribeiro Freire, Johanna Odenwald, Janaina de Freitas Nascimento, Fabiola Holetz, Mark Carrington, Susanne Kramer, Martin Zoltner

published 07 Mar 2025

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Evaluation of the antitrypanosomal activity, cytotoxicity and phytochemistry of red Brazilian propolis

Samyah Alanazi, Naif D. Alenzi

published 19 Nov 2024

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A role for a Trypanosoma brucei cytosine RNA methyltransferase homolog in ribosomal RNA processing

Kevin T. Militello, Jennifer Leigh, Matthew Pusateri, Laurie K. Read, Dineen Vogler

published 25 Apr 2024

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Spatial confinement of Trypanosoma brucei in microfluidic traps provides a new tool to study free swimming parasites

Mariana De Niz, Emmanuel Frachon, Samy Gobaa, Philippe Bastin

published 22 Dec 2023

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Adaptation of CUT&RUN for use in African trypanosomes

Geneva Miller, Lindsey M. Rollosson, Carrie Saada, Serenity J. Wade, Danae Schulz

published 21 Nov 2023

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Structure of the T. brucei kinetoplastid RNA editing substrate-binding complex core component, RESC5

Raul Salinas, Emily Cannistraci, Maria A. Schumacher

published 02 Mar 2023

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Prevalence of pathogenic trypanosome species in naturally infected cattle of three sleeping sickness foci of the south of Chad

Joël Vourchakbé, Arnol Auvaker Zebaze Tiofack, Sartrien Tagueu Kante, Padja Abdoul Barka, Gustave Simo

published 30 Dec 2022

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StaR-related lipid transfer-like domain-containing protein CLDP43 affects cardiolipin synthesis and mitochondrial function in Trypanosoma brucei

Alessio Loffreda, Michael Schlame, Peter Bütikofer

published 22 Apr 2022

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The EIF4E1-4EIP cap-binding complex of Trypanosoma brucei interacts with the terminal uridylyl transferase TUT3

Franziska Falk, Kevin Kamanyi Marucha, Christine Clayton

published 22 Nov 2021

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Single nucleotide polymorphisms and copy-number variations in the Trypanosoma brucei repeat (TBR) sequence can be used to enhance amplification and genotyping of Trypanozoon strains

Nick Van Reet, Pati Patient Pyana, Sara Dehou, Nicolas Bebronne, Stijn Deborggraeve, Philippe Büscher

published 25 Oct 2021

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