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Transfection

Omics-aided design genome editing strategy for challenging human immortalized cell models

Patricia Mendoza-Garcia, Benjamin Keith, Markus Nordberg, Ella Quist, Cristina Ferrás, Ghaith M. Hamza, Ramy Elgendy, Stephanie Kay Ashenden, Jordi Chi, Natalie R. van Zuydam, Neil Hattersley, Xiang Zhang

published 12 Feb 2026

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Generation of osteoclast-like cells from human peripheral blood mononuclear cells using NFATc1 modified RNA

Sirada Srihirun, Chareerut Phruksaniyom, Thanaporn Sriwantana, Tipparat Parakaw, Nathawut Sibmooh, Pornpun Vivithanaporn, Kran Suknuntha

published 11 Feb 2026

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A novel approach towards a histone replacement system in Tetrapods

Maximilian Pfisterer, Amelie Pritz, Anna Parry, M. Lienhard Schmitz

published 10 Feb 2026

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MicroRNA-488-3p-loaded engineered exosomes inhibit proliferation, migration and invasion of hepatocellular carcinoma by targeting SEC61G

Huijie Gao, Zhaobin He, Shengbiao Yang, Xiqiang Wang, Qisen Yan, Chao Gao, Naiqing Liu, Zhaoyang Zhang, Weibo Niu, Jun Niu, Cheng Peng

published 09 Feb 2026

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Regulation of tension-dependent localization of LATS1 and LATS2 to adherens junctions

Chamika De Silva, Brian A. Kelch, Dannel McCollum

published 02 Feb 2026

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Iodine increases pulmonary type I interferon responses and decreases covid-19 disease severity: Results from an open label randomized clinical trial

René Traksel, Jasper Broen, Arjen van Henten, Marc Königs, Arjun Raj, Laura van Eyndhoven, Richard Verheesen

published 02 Feb 2026

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Enarodustat suppresses thymic stromal lymphopoietin expression via hypoxia-inducible factor-mediated c-Jun N-terminal kinases dephosphorylation

Ryosuke Segawa, Makiko Yagisawa, Chihiro Miyata, Noriyasu Hirasawa

published 23 Jan 2026

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Evaluation of rat pancreatic islets damage after siRNA microporation

Veronika Tomsovska, Ivan Leontovyc, Klara Zacharovova, Eva Fabryova, Tomas Koblas, Zuzana Berkova, Jan Kriz

published 23 Jan 2026

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RIPK2 induces docetaxel resistance in prostate cancer through the NF-κB/P-gp signaling pathway

Shaoqiang Xing, Zhaoliang Xu, Sheng Zeng, Minghao Yue, Wenzhou Xing, Qian Liu

published 21 Jan 2026

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Lethal effect of heterologous Haemonchus contortus α- and β-tubulin expression in Leishmania tarentolae

Marc Borchert, Jürgen Krücken, Marion Müller, Georg von Samson-Himmelstjerna

published 15 Jan 2026

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Characteristics of spatiotemporal distribution of HIV-1 Gag-containing complexes on the dorsal membrane tracking with live confocal imaging

Xiao Wang, Xinye An, Hongmei Zhao, Dakang Sun

published 29 Dec 2025

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Deciphering the pathogenicity of three NKX2-1 variants in ultra-severe forms of childhood interstitial lung disease

Yohan David Soreze, Tifenn Desroziers-Louedec, Aurore Carré, Farah Diab, Aphrodite Daskalopoulou, Julie Starck, Valérie Nau, Marie Legendre, Sonia-Athina Karabina, Véronique Houdouin, Aurore Coulomb-L’herminé, Camille Louvrier, Nadia Nathan

published 19 Dec 2025

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Anticodon-edited tRNA enables translational readthrough of COL4A5 premature termination codons

Kohei Omachi, Joseph J. Porter, John D. Lueck, Jeffrey H. Miner

published 19 Dec 2025

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