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Transcriptome analysis

Single-cell RNA-seq data normalization: A benchmarking study

Qinyu Ge, Yuqi Sheng, Junru Lu, Yuwei Yang, Min Pan

published 18 Dec 2025

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Co-regulation of microglial subgroups in Alzheimer’s amyloid pathology: Implications for diagnosis and drug development

Yu Zhou, Yukuan Huang, Yangchang Fan, Feng Xue

published 05 Dec 2025

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Decoding the distinct immune landscape and possible regulatory mechanisms of autoimmune hepatitis through integrated single-cell and bulk RNA sequencing

Gang Chi, Yijia Che, Jinhong Pei, Xueqing Li, Junmei Wang

published 04 Dec 2025

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Targeted fetal NGS panel reveals genetic conditions in sonographically normal fetuses: Insights from a large cohort study

Han-Ying Chen, Yi-Ting Wang, Jessica Kang, Yi-Yun Tai, Ti-Jia Yuan, Shin-Yu Lin, Shi-Ming Lin, Chien-Nan Lee, Tsang-Ming Ko

published 02 Dec 2025

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Early upregulation of immune suppressors dominates the macrophage response to Toxoplasma gondii

Dominykas Murza, Filip Lastovka, George Wood, Matthew P. Brember, Oliver Chan, James W. Ajioka, Betty Y. W. Chung

published 24 Nov 2025

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Single-cell transcriptomics profiling reveals cellular origins and molecular drivers underlying melanoma brain metastasis

Jingxin Zeng, Ling Lin, Yangyang Ma, Wenzhe Huang, Quan Luo, Ju Wen

published 24 Nov 2025

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Multi-omics analysis indicates an association between TAPBP and prostate cancer

Xinlong Wang, Aimin Jiang, Chao Li, Zhiyong Liu

published 21 Nov 2025

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Genome- and transcriptome-wide association meta-analysis reveals new insights into genes affecting coronary and peripheral artery disease

Michael Rode, Maciej Rosolowski, Katrin Horn, Sylvia Henger, Andrej Teren, Kerstin Wirkner, Joachim Thiery, Markus Loeffler, Janne Pott, Holger Kirsten, Markus Scholz

published 18 Nov 2025

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Transcriptomics insights into the functional role of tick Ixodes ricinus proteins metalloprotease and antigen p23

Rita Vaz-Rodrigues, Vincent C. Duru, Ard M. Nijhof, José de la Fuente

published 14 Nov 2025

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Development of SSR markers related to salinity resistance based on transcriptomic sequences in Medicago sativa

Rugang Yu, Xin Chen, Hui Zhang, Qiting Zhang, Xinyi Chen, Yanqiu Dong, Liwei Chen, Daniel Basigalup, Guoliang Wang, Xueling Du

published 14 Nov 2025

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ReadSeeker: A DNABERT based de-novo read-level gene predictor

Ben Wulf, Piotr Wojciech Dabrowski

published 13 Nov 2025

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Multi-omics analysis reveals metabolic regulation of phosphatidylcholine, triglycerides, phosphatidylethanolamine, and cardiolipin metabolism in mouse liver with metabolic dysfunction-associated steatotic liver disease

Hong Liang, Kang Song

published 07 Nov 2025

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A joint complex network and machine learning approach for the identification of discriminative gene communities in autistic brain

Antonio Lacalamita, Ester Pantaleo, Alfonso Monaco, Loredana Bellantuono, Alessandro Fania, Marianna La Rocca, Tommaso Maggipinto, Sabina Tangaro, Nicola Amoroso, Roberto Bellotti

published 05 Nov 2025

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