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Structure-based discovery of a novel Granzyme A (GZMA) inhibitor for autism spectrum disorder through integrative transcriptomics, virtual screening, and long-timescale molecular dynamics simulations
published 13 Oct 2026
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Single-cell transcriptomics and machine learning characterize LTA4H-linked lipid metabolism and inflammatory signatures in the knee osteoarthritis IPFP/synovium compartment
published 12 Oct 2026
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Integrated bioinformatics analysis identifies an immune-related gene signature associated with non-obstructive azoospermia
published 12 Oct 2026
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Benchmarking ensemble and deep learning models for drought-responsive gene prioritisation in rice using multi-omics data
published 09 Oct 2026
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Intercellular GAS6-AXL signaling triggers podocyte cuproptosis in acute kidney injury upstream regulated by CEBPD
published 09 Oct 2026
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Transcriptomic analysis of zebrafish (Danio rerio) liver exposed to sediments from the Loa River
published 09 Oct 2026
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Identification of shared diagnostic biomarkers and immune-related mechanisms between sepsis and thoracic aortic aneurysm based on integrated bioinformatics and machine learning approaches
published 08 Oct 2026
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Genomic diversity, host associations, and tissue tropism of Hydrangea ringspot virus: A global and regional perspective
published 08 Oct 2026
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Integrative transcriptomics identifies an 18-gene candidate blood-accessible biomarker panel for longitudinal monitoring of spaceflight-induced muscle atrophy
published 07 Oct 2026
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Shenling Qige Granules inhibit esophageal squamous cell carcinoma progression in TE-1 xenograft and cell-based models by modulating the DCN–TGF-β/Smad signaling axis
published 06 Oct 2026
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Integrated multi-omic analysis characterizes an IFNγ-responsive-to-myeloid-suppressive immune continuum in immune-active hepatocellular carcinoma
published 06 Oct 2026
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GP-DHT: A dual-head transformer with supervised contrastive learning for shared-gene pretraining and single-cell GRN prediction
published 06 Oct 2026
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Rigorous validation of graph-based network analysis reappraises biologically coherent ADHD-associated transcriptomic modules in peripheral blood
published 05 Oct 2026
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