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Transactivation

Deciphering the pathogenicity of three NKX2-1 variants in ultra-severe forms of childhood interstitial lung disease

Yohan David Soreze, Tifenn Desroziers-Louedec, Aurore Carré, Farah Diab, Aphrodite Daskalopoulou, Julie Starck, Valérie Nau, Marie Legendre, Sonia-Athina Karabina, Véronique Houdouin, Aurore Coulomb-L’herminé, Camille Louvrier, Nadia Nathan

published 19 Dec 2025

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Mis-splicing drives loss of function of p53^E224D point mutation

Ian C. Lock, Nathan H. Leisenring, Warren Floyd, Eric S. Xu, Lixia Luo, Yan Ma, Erin C. Mansell, Diana M. Cardona, Chang-Lung Lee, David G. Kirsch

published 05 Mar 2025

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Differential gene regulation by a synthetic vitamin D receptor ligand and active vitamin D in human cells

Miho Iwaki, Yoshiaki Kanemoto, Takahiro Sawada, Koki Nojiri, Tomohiro Kurokawa, Rino Tsutsumi, Kazuo Nagasawa, Shigeaki Kato

published 13 Dec 2023

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S-1-propenyl-L-cysteine suppresses lipopolysaccharide-induced expression of matrix metalloproteinase-1 through inhibition of tumor necrosis factor-α converting enzyme-epidermal growth factor receptor axis in human gingival fibroblasts

Hiroshi Nango, Masahiro Ohtani

published 21 Apr 2023

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The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs

Simon Lind, Kenneth L. Granberg, Huamei Forsman, Claes Dahlgren

published 06 Apr 2023

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Jagged1 intracellular domain modulates steroidogenesis in testicular Leydig cells

Sudeep Kumar, Hee-Sae Park, Keesook Lee

published 30 Dec 2020

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DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene

Mery Giantin, Jenni Küblbeck, Vanessa Zancanella, Viktoria Prantner, Fabiana Sansonetti, Axel Schoeniger, Roberta Tolosi, Giorgia Guerra, Silvia Da Ros, Mauro Dacasto, Paavo Honkakoski

published 25 Mar 2019

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Role of FOXC2 and PITX2 rare variants associated with mild functional alterations as modifier factors in congenital glaucoma

Cristina Medina-Trillo, José-Daniel Aroca-Aguilar, Jesús-José Ferre-Fernández, Susana Alexandre-Moreno, Laura Morales, Carmen-Dora Méndez-Hernández, Julián García-Feijoo, Julio Escribano

published 18 Jan 2019

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PKM2 and HIF-1α regulation in prostate cancer cell lines

Diya Hasan, Elisabetta Gamen, Nafez Abu Tarboush, Yazan Ismail, Oleg Pak, Belal Azab

published 14 Sep 2018

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Effect of combining glucocorticoids with Compound A on glucocorticoid receptor responsiveness in lymphoid malignancies

Dorien Clarisse, Karlien Van Wesemael, Jan Tavernier, Fritz Offner, Ilse M. Beck, Karolien De Bosscher

published 08 May 2018

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p73, like its p53 homolog, shows preference for inverted repeats forming cruciforms

Jana Čechová, Jan Coufal, Eva B. Jagelská, Miroslav Fojta, Václav Brázda

published 18 Apr 2018

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The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries

Xuan Yu, John N. Stallone, Cristine L. Heaps, Guichun Han

published 23 Jan 2018

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An extract from date palm fruit (Phoenix dactylifera) acts as a co-agonist ligand for the nuclear receptor FXR and differentially modulates FXR target-gene expression in vitro

Emilia Alfaro-Viquez, Brent F. Roling, Christian G. Krueger, Charlene J. Rainey, Jess D. Reed, Marie-Louise Ricketts

published 02 Jan 2018

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