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Small molecules

Effects of 39 Compounds on Calmodulin-Regulated Adenylyl Cyclases AC1 and Bacillus anthracis Edema Factor

Carolin Lübker, Roland Seifert

Murine Efficacy and Pharmacokinetic Evaluation of the Flaviviral NS5 Capping Enzyme 2-Thioxothiazolidin-4-One Inhibitor BG-323

Kristen M. Bullard, Rebekah C. Gullberg, [ ... ], Susan M. Keenan

Discovery of allosteric regulators with clinical potential to stabilize alpha-L-iduronidase in mucopolysaccharidosis type I

Elena Cubero, Ana Ruano, [ ... ], Ana Maria Garcia-Collazo

A compound attributes-based predictive model for drug induced liver injury in humans

Yang Liu, Hua Gao, Yudong D. He

Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics

Richard L. Cullum, Lauren M. Lucas, [ ... ], David J. Riese, II

Side-by-side comparison of published small molecule inhibitors against thapsigargin-induced store-operated Ca²⁺ entry in HEK293 cells

Katherine Norman, Karen E. Hemmings, [ ... ], Marc A. Bailey

Peritoneal dialysis modality transition and impact on phosphate and potassium serum levels

Daniela Peruzzo, Murilo Guedes, [ ... ], on behalf of the BRAZPD Investigators

Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

Frances M. Bashore, Vittorio L. Katis, [ ... ], Alison D. Axtman

Small molecules targeting LapB protein prevent Listeria attachment to catfish muscle

Ali Akgul, Nawar Al-Janabi, [ ... ], Attila Karsi

Quantifying the Tendency of Therapeutic Target Proteins to Bind Promiscuous or Selective Compounds

Ye Hu, Jürgen Bajorath

Efficacy of a small molecule inhibitor of the transcriptional cofactor PC4 in prevention and treatment of non-small cell lung cancer

Yan Zhang, Andrei Pavlov, [ ... ], Hui Ge

High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells

Danielle L. Schmitt, Patricia Dranchak, [ ... ], Songon An

Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryonic stem cells

Cameron Sadegh, Wataru Ebina, [ ... ], Jeffrey D. Macklis

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