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Small molecules

Xanthene Food Dye, as a Modulator of Alzheimer's Disease Amyloid-beta Peptide Aggregation and the Associated Impaired Neuronal Cell Function

H. Edward Wong, Inchan Kwon

Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity

Elizabeth R. Sharlow, Gabriela Mustata Wilson, [ ... ], John S. Lazo

A Systems Approach for Tumor Pharmacokinetics

Greg Michael Thurber, Ralph Weissleder

Acute Drug Treatment in the Early C. elegans Embryo

Ana Carvalho, Sara K. Olson, [ ... ], Karen Oegema

High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model

Joost Schulte, Katharine J. Sepp, [ ... ], J. Troy Littleton

Efficient Non-Viral Reprogramming of Myoblasts to Stemness with a Single Small Molecule to Generate Cardiac Progenitor Cells

Zeeshan Pasha, Husnain Kh Haider, Muhammad Ashraf

Comprehensive Structural and Substrate Specificity Classification of the Saccharomyces cerevisiae Methyltransferome

Tomasz Wlodarski, Jan Kutner, [ ... ], Krzysztof Ginalski

Live-Cell Microscopy Reveals Small Molecule Inhibitor Effects on MAPK Pathway Dynamics

Daniel J. Anderson, Jenni K. Durieux, [ ... ], Mary J. C. Ludlam

Benchmarking and Analysis of Protein Docking Performance in Rosetta v3.2

Sidhartha Chaudhury, Monica Berrondo, [ ... ], Jeffrey J. Gray

Resistance to the CCR5 Inhibitor 5P12-RANTES Requires a Difficult Evolution from CCR5 to CXCR4 Coreceptor Use

Rebecca Nedellec, Mia Coetzer, [ ... ], Donald E. Mosier

Stage-Related Alterations in Renal Cell Carcinoma – Comprehensive Quantitative Analysis by 2D-DIGE and Protein Network Analysis

Heike Junker, Simone Venz, [ ... ], Reinhard Walther

Why CCR2 and CCR5 Blockade Failed and Why CCR1 Blockade Might Still Be Effective in the Treatment of Rheumatoid Arthritis

Maria C. Lebre, Clarissa E. Vergunst, [ ... ], Paul P. Tak

Integrated Bio-Entity Network: A System for Biological Knowledge Discovery

Lindsey Bell, Rajesh Chowdhary, [ ... ], Jinfeng Zhang

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