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Small molecules

A Systems Approach for Tumor Pharmacokinetics

Greg Michael Thurber, Ralph Weissleder

published 14 Sep 2011

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Acute Drug Treatment in the Early C. elegans Embryo

Ana Carvalho, Sara K. Olson, Edgar Gutierrez, Kelly Zhang, Lisa B. Noble, Esther Zanin, Arshad Desai, Alex Groisman, Karen Oegema

published 14 Sep 2011

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High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model

Joost Schulte, Katharine J. Sepp, Chaohong Wu, Pengyu Hong, J. Troy Littleton

published 31 Aug 2011

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Efficient Non-Viral Reprogramming of Myoblasts to Stemness with a Single Small Molecule to Generate Cardiac Progenitor Cells

Zeeshan Pasha, Husnain Kh Haider, Muhammad Ashraf

published 17 Aug 2011

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Comprehensive Structural and Substrate Specificity Classification of the Saccharomyces cerevisiae Methyltransferome

Tomasz Wlodarski, Jan Kutner, Joanna Towpik, Lukasz Knizewski, Leszek Rychlewski, Andrzej Kudlicki, Maga Rowicka, Andrzej Dziembowski, Krzysztof Ginalski

published 09 Aug 2011

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Live-Cell Microscopy Reveals Small Molecule Inhibitor Effects on MAPK Pathway Dynamics

Daniel J. Anderson, Jenni K. Durieux, Kyung Song, Ryan Alvarado, Peter K. Jackson, Georgia Hatzivassiliou, Mary J. C. Ludlam

published 04 Aug 2011

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Benchmarking and Analysis of Protein Docking Performance in Rosetta v3.2

Sidhartha Chaudhury, Monica Berrondo, Brian D. Weitzner, Pravin Muthu, Hannah Bergman, Jeffrey J. Gray

published 02 Aug 2011

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Resistance to the CCR5 Inhibitor 5P12-RANTES Requires a Difficult Evolution from CCR5 to CXCR4 Coreceptor Use

Rebecca Nedellec, Mia Coetzer, Michael M. Lederman, Robin E. Offord, Oliver Hartley, Donald E. Mosier

published 08 Jul 2011

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Stage-Related Alterations in Renal Cell Carcinoma – Comprehensive Quantitative Analysis by 2D-DIGE and Protein Network Analysis

Heike Junker, Simone Venz, Uwe Zimmermann, Andrea Thiele, Christian Scharf, Reinhard Walther

published 07 Jul 2011

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Why CCR2 and CCR5 Blockade Failed and Why CCR1 Blockade Might Still Be Effective in the Treatment of Rheumatoid Arthritis

Maria C. Lebre, Clarissa E. Vergunst, Ivy Y. K. Choi, Saïda Aarrass, Ana S. F. Oliveira, Tim Wyant, Richard Horuk, Kris A. Reedquist, Paul P. Tak

published 01 Jul 2011

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Integrated Bio-Entity Network: A System for Biological Knowledge Discovery

Lindsey Bell, Rajesh Chowdhary, Jun S. Liu, Xufeng Niu, Jinfeng Zhang

published 27 Jun 2011

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Tyrosine Kinase Syk Non-Enzymatic Inhibitors and Potential Anti-Allergic Drug-Like Compounds Discovered by Virtual and In Vitro Screening

Bruno O. Villoutreix, Guillaume Laconde, David Lagorce, Pierre Martineau, Maria A. Miteva, Piona Dariavach

published 20 Jun 2011

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p53 Transactivation and the Impact of Mutations, Cofactors and Small Molecules Using a Simplified Yeast-Based Screening System

Virginia Andreotti, Yari Ciribilli, Paola Monti, Alessandra Bisio, Mattia Lion, Jennifer Jordan, Gilberto Fronza, Paola Menichini, Michael A. Resnick, Alberto Inga

published 02 Jun 2011

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