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Small interfering RNA

The Hippo-YAP/β-catenin signaling axis coordinates odontogenic differentiation in dental pulp stem cells: Implications for dentin-pulp regeneration

Chang Chen, Qiqi Yun, Juanli Ran, Ziyao Zhou, Pengxiang Zhang, Rong Li

published 26 Jun 2025

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SNAI2 cooperates with MEK1/2 and HDACs to suppress BIM- and BMF-dependent apoptosis in TERT promoter mutant cancers

Amol Tandon, Josh Lewis Stern

published 25 Jun 2025

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Prostaglandin E₂ dependent migration of human brain endothelial cells is mediated through Rho-Kinase-II

Gausal Azam Khan, Arjun Ghosh

published 23 Jun 2025

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AKR1C2 silencing promotes ferroptosis and inhibits proliferation, migration, and invasion in lung cancer cells

Yi Cui, Zhihui Liu

published 18 Jun 2025

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Effect of retinoic acid treatment on the retinoic acid signaling pathway in a human siRNA-based aniridia limbal epithelial cell model, in vitro

Shao-Lun Hsu, Tanja Stachon, Fabian N. Fries, Zhen Li, Shuailin Li, Shanhe Liu, Berthold Seitz, Swarnali Kundu, Maryam Amini, Shweta Suiwal, Nóra Szentmáry

published 18 Jun 2025

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Gene expression study in the siRNA based aniridia cell model and in primary aniridia limbal epithelial cells following duloxetine and ritanserin treatment

Shweta Suiwal, Tanja Stachon, Zhen Li, Marta Corton, Mahsa Nastaranpour, Ning Chai, Maryam Amini, Berthold Seitz, Fabian N. Fries, Thomas Tschernig, Nóra Szentmáry

published 10 Jun 2025

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The tumor suppressor FAT1 controls YAP/TAZ protein degradation and tumor cell proliferation through E3 ligase MIB2

Rui Li, Boris Strilic, Young-June Jin, Jingchen Shao, Yundong Peng, Lei Wang, Qi Quan, Zhiyong Wang, Johannes Graumann, J. Silvio Gutkind, Nina Wettschureck, Stefan Offermanns

published 06 Jun 2025

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Human umbilical cord mesenchymal stem cell-derived exosomes mitigate acute radiation-induced intestinal oxidative damage via the Nrf2/HO-1/NQO1 signaling pathway

Hongyu Wang, Jinbao Wang, Gaosheng Yang, Yanjie Li, Weikai Chen, Jianping Yu, Xiaopeng Han

published 06 Jun 2025

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RNA-mediated gene silencing can reduce azole resistance, growth and pathogenicity in Pseudocercospora fijiensis

Flor Yuranny Canacuán Melo, Yohana Katerine Suárez Anaya, Vicente Emilio Rey Valenzuela, Juan Gonzalo Morales Osorio, Rafael Eduardo Arango Isaza

published 05 Jun 2025

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Two cancer cell lines utilize Myosin 10 and the kinesin HSET differentially to maintain mitotic spindle bipolarity

Yang-In Yim, Xufeng Wu, Anjelika Gasilina, John A. Hammer

published 29 May 2025

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Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells

Mi Huang, Duanzhuo Li, Zhengzhen Xia, Shengjie Liao, Wenxia Si, Chao Yuan, Yanli Liao, Weibin Wu, Minshu Jiang, Xin Yu, Yi Quan

published 22 May 2025

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Downregulation of OIP5-AS1 inhibits apoptosis in myocardial ischemia/reperfusion injury via modulating the MiR-145-5p/ROCK1 axis

Jingyan Yang, Jing Liu, Xiaobo Liu, Dongling Xu, Juan Zhang

published 20 May 2025

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Leishmania regulates host YY1: Comparative proteomic analysis identifies infection modulated YY1 dependent proteins

Harsimran Kaur Brar, Eleanor Chen, Fabian Chang, Shawna Angel Lu, Dilraj Kaur Longowal, Kyung-Mee Moon, Leonard J. Foster, Neil Reiner, Devki Nandan

published 15 May 2025

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