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Small interfering RNA

LSR overexpression induces chemoresistance in triple negative breast cancer cells through MDR1 upregulation and apoptosis attenuation

Ming Zhao, Zhikun Ma, Amanda B. Parris, Xiaohe Yang

published 03 Nov 2025

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STAG2 regulates polycomb and differentiation in urothelial precursors and bladder cancer

Youngrok Park, Wanying Xu, Tianyi Yang, Victoria Hill, Xiaoyuan He, Lisa Sadzewicz, Luke Tallon, Jung-Sik Kim, Fulai Jin, Todd Waldman

published 15 Oct 2025

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Exploring the impact of antibody-dependent cellular phagocytosis-related genes on the prognosis of metastatic melanoma

Junhao Chen, Jiapeng He, Xiaolong Xu, Haiyan Sun, Jianglin Zhang

published 09 Oct 2025

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Caveolin-1 knockout improves CFA-induced inflammatory pain in adult mice through modulating the cGAS STING pathway and autophagy

Huan Chang, Cancan Cheng, Ning Zheng, Haiyan Zhu, Hui Yang, Xiaocheng Zhu, Fan Zhang

published 09 Oct 2025

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Integrated analysis of ARHGAP6 potential function and prognostic value in acute myeloid leukemia

Debin Yang, Yuanzhe Li, Ping Ma, Fankai Xiao

published 07 Oct 2025

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MHC-mismatched synovial mesenchymal stem cell injections delay knee osteoarthritis progression through hepatocyte growth factor secretion in rats

Tsukasa Kitahashi, Kentaro Nakamura, Ryo Kogawa, Ichiro Sekiya

published 03 Oct 2025

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Super-enhancer-associated LINC00963 promotes metastasis of gastric cancer through epithelial-mesenchymal transition

Hong Du, Tingting Xiang, Ying Xia, Yong Jin, Fahua Deng, Wansong Xia, Hongyu Li, Shuqiang Cheng, Bingxue Lan, Sixi Wei, Cunfeng Song, Hai Huang

published 18 Sep 2025

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Validation of blue- and clear-native polyacrylamide gel electrophoresis protocols to characterize mitochondrial oxidative phosphorylation complexes

Jana Aref, Seungtae Lee, Supachaya Sriphoosanaphan, Micol Falabella, Shi-Yu Yang, Jan-Willem Taanman

published 18 Sep 2025

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Cleavage of MALAT1 RNA by 14-nt sgRNA-guided tRNase Z^L

Masayuki Takahashi, Masayuki Nashimoto

published 18 Sep 2025

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C3AR1 may aggravate diabetic nephropathy by mediating oxidative stress via ITGB2 regulation in renal tubular epithelial cells

Alex Abura, Shan Gao

published 12 Sep 2025

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TGFBR1 gene silencing attenuates cardiomyopathy in the HFpEF mouse model

Xuanyang Shen, Weidong Li, Xiaolu Jiang, Hongfu Wen, Yuan Shen, Wen Zhang, Yongjian Peng, Guoping Kang

published 29 Aug 2025

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Piezo1 regulates autophagy in HT22 hippocampal neurons through the Ca²⁺/Calpain and Calcineurin/TFEB signaling pathways

Yatong Wu, Yan Lu, Hao Zhang, Suhe Dong, Ziqing Zhang, Sinian Wang, Fengsheng Li, Shimin Yin

published 26 Aug 2025

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Downregulation of NCOA4 expression indicates poor prognosis and promotes the progression of cholangiocarcinoma

Wenlong Shen, Yi Liu, Bing Dai, Changling Qin, Yongli Fu, Xi Li, Chi Liu

published 11 Aug 2025

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