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SH2 domains

Role of two modules controlling the interaction between SKAP1 and SRC kinases comparison with SKAP2 architecture and consequences for evolution

Laurine Levillayer, Camille Brighelli, [ ... ], Jean-François Bureau

SHP-1 tyrosine phosphatase binding to c-Src kinase phosphor-dependent conformations: A comparative structural framework

Mehreen Gul, Ahmad Navid, Muhammad Fakhar, Sajid Rashid

High prevalence of low-allele-fraction somatic mutations in STAT3 in peripheral blood CD8+ cells in multiple sclerosis patients and controls

Miko Valori, Joonas Lehikoinen, [ ... ], Pentti Tienari

The SH2 domain and kinase activity of JAK2 target JAK2 to centrosome and regulate cell growth and centrosome amplification

Aashirwad Shahi, Jacob Kahle, Chandler Hopkins, Maria Diakonova

NHD2-15, a novel antagonist of Growth Factor Receptor-Bound Protein-2 (GRB2), inhibits leukemic proliferation

Tina R. Lewis, Jesse Smith, [ ... ], Carolynn C. Arpin

Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide

Rachel Jaber Chehayeb, Amy L. Stiegler, Titus J. Boggon

Identification of novel small molecules that inhibit STAT3-dependent transcription and function

Iryna Kolosenko, Yasmin Yu, [ ... ], Dan Grander

Inhibition of STAT3 by Anticancer Drug Bendamustine

Kazunori Iwamoto, Yutaka Uehara, [ ... ], Akira Asai

SmShb, the SH2-Containing Adaptor Protein B of Schistosoma mansoni Regulates Venus Kinase Receptor Signaling Pathways

Marion Morel, Mathieu Vanderstraete, [ ... ], Colette Dissous

Crystal Structure of the FERM-SH2 Module of Human Jak2

Randall McNally, Angela V. Toms, Michael J. Eck

Tyrosine Phosphorylation of Caspase-8 Abrogates Its Apoptotic Activity and Promotes Activation of c-Src

Jennifer LY Tsang, Song Hui Jia, [ ... ], John C. Marshall

A Central Nervous System-Dependent Intron-Embedded Gene Encodes a Novel Murine Fyn Binding Protein

Noureddine Ben Khalaf, Safa Taha, Moiz Bakhiet, M. Dahmani Fathallah

How Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5

Florent Langenfeld, Yann Guarracino, [ ... ], Luba Tchertanov

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